interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF THE LAC REPRESSOR BOUND TO ONPG IN REPRESSED STATE
(Lactose operon repressor)
referenceStayrook et al. J.Mol.Biol. 370 609 2007
sourceEscherichia coli
experimentX-ray (resolution=3.50, R-factor=0.236)
structural superfamilyPeriplasmic binding protein-like I;lambda repressor-like DNA-binding domains;
sequence familyBacterial regulatory proteins, lacI fami; Periplasmic binding proteins and sugar b;
multimeric complexes1cjg_AB 1efa_AB 1jwl_AB 1l1m_AB 1lbg_AB 1lbg_CD 1osl_AB 2bjc_AB 2kei_AB 2kej_AB 2kek_AB 2pe5_AB
reference complex1l1m_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureLYSYQSRALA

Estimated binding specificities ?

readout + contactlogo
# IC=6.915 IC/col=0.988 n_of_columns=7 specificity:   
A |  12   0   0  12   0  84   0
C |  60   0  96  12  96  12  96
G |  12  96   0  12   0   0   0
T |  12   0   0  60   0   0   0
scan!

home
updated Thu Jan 8 20:31:53 2026