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structure nameCRYSTAL STRUCTURE OF THE LAC REPRESSOR BOUND TO ONPG IN REPRESSED STATE
(Lactose operon repressor)
referenceStayrook et al. J.Mol.Biol. 370 609 2007
sourceEscherichia coli
experimentX-ray (resolution=3.50, R-factor=0.236)
structural superfamilyPeriplasmic binding protein-like I;lambda repressor-like DNA-binding domains;
sequence familyBacterial regulatory proteins, lacI fami; Periplasmic binding proteins and sugar b;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureLYSYQSRALA

Estimated binding specificities ?

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# IC=6.766 IC/col=0.967 n_of_columns=7 specificity:   
A |   0   0   0  64   0   0  10
C |   0   0   0  10   0  85  10
G |  96  10  96  10  96  10  66
T |   0  86   0  12   0   1  10
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updated Mon Dec 16 19:59:40 2024