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structure nameCRYSTAL STRUCTURE OF THE LAC REPRESSOR BOUND TO ONPG IN REPRESSED STATE
(Lactose operon repressor)
referenceStayrook et al. J.Mol.Biol. 370 609 2007
sourceEscherichia coli
experimentX-ray (resolution=3.50, R-factor=0.236)
structural superfamilyPeriplasmic binding protein-like I;lambda repressor-like DNA-binding domains;
sequence familyBacterial regulatory proteins, lacI fami; Periplasmic binding proteins and sugar b;
multimeric complexes1efa_AB 1jwl_AB 1lbg_AB 1lbg_CD 2pe5_AB
reference complex1efa_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureLYSYQSRALA

Estimated binding specificities ?

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# IC=6.915 IC/col=0.988 n_of_columns=7 specificity:   
A |  12   0   0  12   0  84   0
C |  60   0  96  12  96  12  96
G |  12  96   0  12   0   0   0
T |  12   0   0  60   0   0   0
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updated Thu Sep 12 16:27:00 2024