2xro_E : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF TTGV IN COMPLEX WITH ITS DNA OPERATOR (HTH-TYPE TRANSCRIPTIONAL REGULATOR TTGV)
reference	Gallegos et al. 'Genes 24 2556 2010
source	PSEUDOMONAS PUTIDA
experiment	X-ray (resolution=3.40, R-factor=0.217)
structural superfamily	GAF domain-like;"Winged helix" DNA-binding domain;
sequence family	IclR helixturnhelix domain; Bacterial transcriptional regulator;
multimeric complexes	2xro_ABEF
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 2xro_E interface=22,33,34,35,37,38, qviaraasimralgshphglsLaaiaqlvglpRSTvQRiinaleeeflvealgpaggfrlgpalgqlinqaqtdilslvkpylrslaeeldesvslaslagdkiyvldrivserelrvvfpiginvpaaataagkvllaalpdetlqaalgeqlpvltsntlgrkalvkqlsevrqsgvasdldehidgvssfatlldtylgyyslaivmpssraskqsdlikkallqsklnieraigr
interface signature	LRSTQR

Estimated binding specificities ?

readout + contact

# IC=4.475 IC/col=0.895 n_of_columns=5

specificity:

A |   0   0  16  13  96
C |  96   0  13  13   0
G |   0  96  54  13   0
T |   0   0  13  57   0

scan!

Dendrogram of similar interfaces ?

matrix format

  
  LTRTSGTGQTRG------------------   L            +-------------------2xro_E    
                                           +----1 
  ----------RCYG------KT--------         +-2    +-------------------2acj_B    
                                         ! ! 
  ------------YG----------------       +-3 +------------------------3eyi_B    
                                       ! ! 
  TT--KATTQTTGLTRTKA----FTYT----   L --4 +--------------------------2p7c_B    
                                       ! 
  ----------NC------IT--NA--RGRG   L   +---------------------------6fqq_E

home
updated Mon Jun 29 15:46:31 2026