2xro_E : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF TTGV IN COMPLEX WITH ITS DNA OPERATOR (HTH-TYPE TRANSCRIPTIONAL REGULATOR TTGV)
reference	Gallegos et al. 'Genes 24 2556 2010
source	PSEUDOMONAS PUTIDA
experiment	X-ray (resolution=3.40, R-factor=0.217)
structural superfamily	GAF domain-like;"Winged helix" DNA-binding domain;
sequence family	IclR helixturnhelix domain; Bacterial transcriptional regulator;
multimeric complexes	2xro_ABEF
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 2xro_E interface=22,33,34,35,37,38, qviaraasimralgshphglsLaaiaqlvglpRSTvQRiinaleeeflvealgpaggfrlgpalgqlinqaqtdilslvkpylrslaeeldesvslaslagdkiyvldrivserelrvvfpiginvpaaataagkvllaalpdetlqaalgeqlpvltsntlgrkalvkqlsevrqsgvasdldehidgvssfatlldtylgyyslaivmpssraskqsdlikkallqsklnieraigr
interface signature	LRSTQR

Estimated binding specificities ?

readout + contact

# IC=4.434 IC/col=0.887 n_of_columns=5

specificity:

A |   0   0  16  16  96
C |  96   0  13  13   0
G |   0  96  54  13   0
T |   0   0  13  54   0

scan!

Dendrogram of similar interfaces ?

matrix format

  
  LTRTSGTGQTRG------------   L          +-------------------2xro_E    
                                   +----1 
  ----------RCYG----KT----       +-2    +-------------------2acj_B    
                                 ! ! 
  ------------YG----------     --3 +------------------------3eyi_B    
                                 ! 
  TT--KATTQTTGLTRTKA--FTYT   L   +--------------------------2p7c_B

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updated Sat Jan 10 05:41:20 2026