3a01_E : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF ARISTALESS AND CLAWLESS HOMEODOMAINS BOUND TO DNA (HOMEODOMAIN-CONTAINING PROTEIN)
reference	Miyazono et al. 'Embo 29 1613 2010
source	DROSOPHILA MELANOGASTER
experiment	X-ray (resolution=2.70, R-factor=0.234)
structural superfamily	Homeodomain-like;
sequence family	Homeobox domain;
multimeric complexes	3a01_AB 3a01_EF
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 3a01_E interface=1,6,10,52,55,56, HpyqnRtppRtsftriqvaelekrfhkqkylasaeraalarglkmtdaqvkTwfQNrrtkwrrqtaee
interface signature	HRRTQN

Estimated binding specificities ?

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# IC=6.234 IC/col=1.039 n_of_columns=6

specificity:

A |   0  38  96   0   0   0
C |  19  20   0   0   0   0
G |   0  19   0   0   0  96
T |  77  19   0  96  96   0

scan!

Related DNA sequences reported in the literature ?

site	source	matches (E-value)
term: clawless
TAATTAA	PubMed	3a01_E(7.92e-06), 3a01_AB(5.68e-10)

Dendrogram of similar interfaces ?

matrix format

  
  RA--IAQTNA----   L                       +-5ego_B    
                             +-------------1 
  RT--NT--NA----   L   +-----2             +-1b72_B    
                       !     ! 
  RT--VTQTNA--RG   L --3     +---------------8ejp_B    
                       ! 
  --RTNT--NAIARG   L   +---------------------4cyc_B

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updated Sat Jan 10 05:44:55 2026