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structure nameSTRUCTURE OF ARISTALESS HOMEODOMAIN IN COMPLEX WITH DNA
(Homeobox protein aristaless)
referenceTakamura et al. 'Embo 29 1613 2010
sourceDrosophila melanogaster
experimentX-ray (resolution=2.25, R-factor=0.228)
structural superfamilyHomeodomain-like;
sequence familyHomeobox domain;
multimeric complexes3a01_AB 3a01_EF
redundant complexes3a01
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRRVQN

Estimated binding specificities ?

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# IC=6.030 IC/col=0.861 n_of_columns=7 specificity:   
A |   6   6  72   0   0  78  72
C |   6   0   6   0   0   6   6
G |   6   6  12   0   0   6   6
T |  78  84   6  96  96   6  12
scan!

Related DNA sequences reported in the literature ?


sitesourcematches (E-value)
term: aristaless
TAATTAAPubMed3lnq_A(5.63e-07)

Dendrogram of similar interfaces ?

matrix format
  
  RT--------ITQCNAMC--   L     +-----------------------------2r5y_A    
                             +-2 
  ----------VA--NAQART   L   ! !                           +-1o4x_A    
                           --3 +---------------------------1 
  ----------VTCCNAQART   L   !                             +-8g87_X    
                             ! 
  --DTRTRGTTKT--------   L   +-----------------------------2o8k_A    
                           

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updated Fri Sep 13 17:24:41 2024