4fcy_B : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF THE BACTERIOPHAGE MU TRANSPOSOSOME (TRANSPOSASE)
reference	Montano et al. Nature 491 413 2012
source	ENTEROBACTERIA PHAGE MU
experiment	X-ray (resolution=3.71, R-factor=0.395)
structural superfamily	Ribonuclease H-like;Homeodomain-like;mu transposase, C-terminal domain;
sequence family	Bacteriophage Mu transposase; Mu DNA binding, I gamma subdomain; Mu transposase, Cterminal;
multimeric complexes	4fcy_AB
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4fcy_B interface=56,57,59,60,63,102,121,122,123,126, drealwskwdnasdsqrrlaekwlpavqaademlnqgistktafatvaghyqvsaSTlRDkyYqvqkfakpdwaaalvsefdedawqfliadylrpekpafRkcyerlelaarehgwsipSRAtaFrriqqldeamvvacregehldamqwingdgylhnvfvrwfngdvirpktwfwqdvktrkilgwrcdvsenidsirlsfmdvvtrygipedfhitidntrgaankwltggapnryrfkvkeddpkglfllmgakmhwtsvvagkgwgqakpverafgvggleeyvdkhpalagaytgpygdravdaelflktlaegvamfnartgretemcggklsfddvfereyartivrkpteeqkrmlllpaeavnvsrkgeftlkvggslkgaknvyynlalmlagvkkvvvrfdpqqlhstvycytldgrficeaeclaaagreyrrrqkqlksatkaaikaqkqmdalevaellp
interface signature	STRDYRSRAF

Estimated binding specificities ?

readout + contact

# IC=9.505 IC/col=0.475 n_of_columns=20

specificity:

A |   0   0   6   0  24  24  24  24  24  24  24  24  24  24   0  53  48  58   0   5
C |   0   0  90   0  24  24  24  24  24  24  24  24  24  24   0  16  16  18  96   1
G |   0   0   0  96  24  24  24  24  24  24  24  24  24  24  96  16  16  10   0  90
T |  96  96   0   0  24  24  24  24  24  24  24  24  24  24   0  11  16  10   0   0

scan!

Dendrogram of similar interfaces ?

matrix format

  
  ------SCTGRTDCYTRGSGRAAA--FT--------------------   L             +---------------------4fcy_B    
                                                               +---2 
  ------------------------------WA--TA--ECRT--RC--   L       +-3   +---------------------7jn3_E    
                                                             ! ! 
  ------------------------------------QGECSG--HCQT         +-4 +-------------------------6rwm_A    
                                                           ! ! 
  ----------------------------------------ECSC--KG         ! !                       +--6vdk_A    
                                                         +-5 +-----------------------1 
  --------------------------------QT----ECRG--QG--   L   ! !                         +--7u32_A    
                                                       --6 ! 
  HGSGRG--HG--RT----STKGRGTTLGNT------------------   L   ! +----------------------------1u78_A    
                                                         ! 
  --SGRGPT--SGRG----------------------------------   L   +----------------------------7bhy_A

home
updated Fri Sep 13 18:11:59 2024