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structure name	A THREE-GATE STRUCTURE OF TOPOISOMERASE IV FROM STREPTOCOCCUS PNEUMONIAE (TOPOISOMERASE IV SUBUNIT B, DNA TOPOISOMERASE 4 SUBUNIT A...)
reference	Sanderson et al. 'Nucleic 41 9911 2013
source	STREPTOCOCCUS PNEUMONIAE
experiment	X-ray (resolution=3.70, R-factor=0.189)
structural superfamily	Type II DNA topoisomerase;Ribosomal protein S5 domain 2-like;ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase;
sequence family	DNA gyrase/topoisomerase IV, subunit A; DNA gyrase B; DNA gyrase B subunit, carboxyl terminus; Histidine kinase, DNA gyrase B, and H; Toprim domain;
multimeric complexes	4i3h_AB
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4i3h_A interface=387,573,633,723, avrkrpgmyigstdgaglhhlvweivdnavdealsdridvtinkdgsltvqdhtveviftilhaggkflhgvgssvvnalsswleveitrdgavykqrfenggkpvttlkkigtapksktgtkvtfmpdatifsttdfkyntiserlnesafllknvtlsltdkrtdeaiefhyengvqdfvsylnedkeiltpvlyfegedngfqvevalqyndgfsdnilsfvnnvrtkdggthetglksaitkvmndyarktgllkekegsdyreglaavlsilvpeehlqfegqtkdklgsplarpvvdgivadkltfflmengelasnlirkaikardareaarkargkltpaqsknpaknelylvegdsaggsakqgrdrkfqailplrgKvintakakmadilkneeintmiytigagvgadfsiedanydkiiimtdadtdgahiqtllltffyrymrplveaghvyialpplykmskgayawdgeleelrlqrykglgemnadqlwettmnpetrtlirvtiedlaraerrvnvlmgdkveprrkwiednvkftleniqnmsledimgerfgrYskyiiqdralpdirdglkpvqrrilysmnkdsntfdksyrksaksvgnimgnfhphgdsSiydamvrmsqnwknreilvemhgnngsmdgdppaamrytearlseiagyllqdiekktvpfawnfddtekeptvlpaafpnllvngstgIsagyatdipphnlaevidaavymidhptakidklmeflpgpdfptgaiiqgrdeikkayetgkgrvvvrskteieklkggkeqiviteipyeinkanlvkkiddvrvnnkvagiaevrdesdrdglriaielkkdantelvlnylfkytdlqinynfnmvaidnftprqvgivpilssyiahrrevilarsrfdkekaekrlhiveglirvisildevialirasenkadakenlkvsydfteeqaeaivtlqlyrltntdvvvlqeeeaelrekiamlaaiigdertmynlmkkelrevkkkfatprlssled

No structural evidence for specific binding to DNA (<4 informative columns)

Dendrogram of similar interfaces ?