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structure name1.98A STRUCTURE OF THIOPHENE1 WITH S.AUREUS DNA GYRASE AND DNA
(DNA GYRASE SUBUNIT B,DNA GYRASE SUBUNIT B,DNA GYRASE...)
referenceStavenger et al. 'Proc. 114 E4492 2017
sourceSTAPHYLOCOCCUS AUREUS
experimentX-ray (resolution=1.98, R-factor=0.155)
structural superfamilyType II DNA topoisomerase;
sequence familyDNA gyrase/topoisomerase IV, subunit A; DNA gyrase B subunit, carboxyl terminus; Toprim domain;
multimeric complexes2xcs_BD 4bul_AC 4plb_BD 5bs3_BD 5npk_bd 6fm4_BD 7fvs_AB 7fvt_AB 7mvs_AB
redundant complexes2xcs_B 4bul_C 4plb_D 5bs3_D 6fm4_B 7fvs_A 7fvt_A 7mvs_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRKYSRI

Estimated binding specificities ?

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# IC=5.766 IC/col=0.641 n_of_columns=9 specificity:   
A |   0   0  24  54   0   0  24  24  13
C |  96   0  24  16   0   0  24  24  54
G |   0  96  24  13  96  96  24  24  16
T |   0   0  24  13   0   0  24  24  13
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Dendrogram of similar interfaces ?

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updated Sun Aug  3 09:39:42 2025