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structure name1.98A STRUCTURE OF THIOPHENE1 WITH S.AUREUS DNA GYRASE AND DNA
(DNA GYRASE SUBUNIT B,DNA GYRASE SUBUNIT B,DNA GYRASE...)
referenceStavenger et al. 'Proc. 114 E4492 2017
sourceSTAPHYLOCOCCUS AUREUS
experimentX-ray (resolution=1.98, R-factor=0.155)
structural superfamilyType II DNA topoisomerase;
sequence familyDNA gyrase/topoisomerase IV, subunit A; DNA gyrase B subunit, carboxyl terminus; Toprim domain;
multimeric complexes2xcr_BD 2xcr_SU 2xcs_BD 4bul_AC 4plb_BD 5bs3_BD 5cdo_ABCD 5cdo_RSTU 5cdq_ABCD 5cdq_RSTU 5cdr_AB 5cdr_CD 5iwi_AB 5iwi_CD 5iwm_ABCD 5npk_bd 6fm4_BD 6fqm_ABCD 6fqm_abcd 6fqv_ABCD 6fqv_RSTU 6qtk_ABCD 6qtp_ABCD 6qx1_ABCD 7fvs_AB 7fvt_AB 7mvs_AB
redundant complexes2xcs 4bul 4plb 5bs3 6fm4 7fvs 7fvt 7mvs
reference complex5iwi_C
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRKYSRI

Estimated binding specificities ?

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# IC=5.807 IC/col=0.645 n_of_columns=9 specificity:   
A |   0   0  24  57   0   0  24  24  13
C |  96   0  24  13   0   0  24  24  54
G |   0  96  24  13  96  96  24  24  13
T |   0   0  24  13   0   0  24  24  16
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Dendrogram of similar interfaces ?

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updated Fri Jan 9 04:14:51 2026