interface graph thumbnail
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structure nameTOPOISOMERASE II-DNA CLEAVAGE COMPLEX, APO
(DNA topoisomerase 2)
referenceSchmidt et al. Nature 465 641 2010
sourceSaccharomyces cerevisiae
experimentX-ray (resolution=2.48, R-factor=0.240)
structural superfamilyType II DNA topoisomerase;
sequence familyDNA gyrase/topoisomerase IV, subunit A;
redundant complexes2rgr_A 3l4k_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence

No structural evidence for specific binding to DNA (<4 informative columns)


Dendrogram of similar interfaces ?

matrix format
  
  --KT------------------SA--------------------EGIGSC--------------------------------                                                                     +-3l4j_A    
                                                                                                                                           +-------------3 
  --KA--DC------------------------------------ECIGSG--------------------------------   L                                             +-----8             +-4fm9_A    
                                                                                                                                     !     ! 
  RAKG----------------QAAG----------------------IGAG--------------------------------   L                                          +--9     +---------------5zen_A    
                                                                                                                                  !  ! 
  --KT----RC------------AT----------------------IC------------RG--------------------   L                                          !  +---------------------2xkk_C    
                                                                                                                                  !  
  --KA------------------SA----------------RG----IG----------------------------------                                              !                        +-2xcr_U    
                                                                                                                               +-10                   +----2 
  RCKT------------------SA----------------RG----IG--QT------------------------------   L                                       !  !           +-------4    +-5npk_d    
                                                                                                                               !  !           !       ! 
  ----YT----------------ST------------------RA--IG----------------------------------                                           !  !         +-6       +------5bs8_A    
                                                                                                                               !  !         ! ! 
  ----YC----------------SG----------------RT----IG----------------------------------                                        +-11  !         ! !              +5iwi_C    
                                                                                                                            !  !  +---------7 +--------------1 
  ------------------------------------------------------------------------------DAKG                                        !  !            !                +6n1p_A    
                                                                                                                            !  !            ! 
  --------RC------------ST----------------------IA----------------------------------                                     +-12  !            +--------------3ksb_B    
                                                                                                                         !  !  !  
  --KT------------------------------------------------------------------------------                                     !  !  +---------------------------5bs8_D    
                                                                                                                      +-13  !  
  --KG------------------------------------------------------------------------------                                  !  !  +----------------------------5iwi_D    
                                                                                                                   +-14  !  
  ----------QA------------------------------NG--------------------------------------                               !  !  +----------------------------7k63_U    
                                                                                                                +-15  !  
  --------------RC--------------------------SG--------------------------------------                            !  !  +----------------------------7cow_T    
                                                                                                                !  !  
  ----------------------------------------------------TAFCAGRC----------------------   L                     +-16  +----------------------------6dg0_A    
                                                                                                             !  !  
  ----------------------------NA----RA--LT------------------------------------------   L                     !  !                 +-----------2a07_J    
                                                                                                          +-17  +-----------------5 
  ----------------DTRGRCTT----KT----------------------------------------------------   L                  !  !                    +-----------2o9l_A    
                                                                                                       +-18  !  
  ------------RC--------------------------------------------------------------------                   !  !  +-----------------------------6l9z_S    
                                                                                                    +-19  !  
  --------------------------KGSA----QAKT--------------------------------------------   L            !  !  +-----------------------------7d3t_D    
                                                                                                 +-20  !  
  --------------------------------------------------------------NCAT----STRA--------             !  !  +-----------------------------1a02_J    
                                                                                              +-21  !  
  --------------------------------------------------------------NCAAAT----RT--------   L      !  !  +-----------------------------1a02_F    
                                                                                           +-22  !  
  ------------------------------------------------------------------NG--AT--STRG----       !  !  +-----------------------------5szx_B    
                                                                                         -23  !  
  ------------------------------------------------------------------NCTT--AT--RG----   L   !  +-----------------------------2dgc_A    
                                                                                           !  
  ------------------------NAST--RTHT----LT------------------------------------------   L   +-----------------------------4lg0_A    
                                                                                         

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updated Fri Sep 13 17:23:38 2024