interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF INTERLEUKIN ENHANCER-BINDING FACTOR 1 BOUND TO DNA
(FORKHEAD BOX PROTEIN K2)
referenceChuang et al. J.Biol.Chem. 281 17400 2006
sourceHOMO SAPIENS
experimentX-ray (resolution=2.40, R-factor=0.233)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyFork head domain;
multimeric complexes2c6y_AB
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureNSRHSLKR

Estimated binding specificities ?

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# IC=4.905 IC/col=0.818 n_of_columns=6 specificity:   
A |   7   9   7   0   0  81
C |   7   7  16  14   0   1
G |   0  73   7   0   0   7
T |  82   7  66  82  96   7
scan!

Dendrogram of similar interfaces ?

matrix format
  
  ----------------NASTRGHT--STLT------   L                          +------7cby_C    
                                                                  +-1 
  ------ST--------NASTRTHT--ST--------   L                +-------2 +------3l2c_A    
                                                          !       ! 
  RT--LA--NTHGTTETYTRG----------------   L            +---3       +--------1f4k_B    
                                                      !   ! 
  ----------RGSTRTSTHG------------RA--   L   +--------4   +----------------3zpl_B    
                                             !        ! 
  --TT--------KATTQTTG--LTRT----KA--FT   L --5        +--------------------2p7c_B    
                                             ! 
  --------------SA----------------RG--       +-----------------------------2xcr_U    
                                           

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updated Fri Sep 13 16:13:51 2024