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structure nameCRYSTAL STRUCTURE OF BZIP TRANSCRIPTION FACTOR PAP1 BOUND TO DNA
(TRANSCRIPTION FACTOR PAP1)
referenceHakoshima et al.
sourceSchizosaccharomyces pombe
experimentX-ray (resolution=2.00, R-factor=?)
structural superfamilyLeucine zipper domain;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRQNRAQFR

Estimated binding specificities ?

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# IC=6.499 IC/col=0.928 n_of_columns=7 specificity:   
A |   8   0   8  96  96   8   8
C |  69   0  11   0   0  87  72
G |   8  96   8   0   0   1   8
T |  11   0  69   0   0   0   8
scan!

Related DNA sequences reported in the literature ?


sitesourcematches (E-value)
term: PAP1
TTACGAATPubMed1gd2_G(1.67e-04), 1gd2_EF(2.89e-04), 1gd2_GH(2.93e-04)
TTACGTATPubMed1gd2_G(1.67e-04), 1gd2_EF(4.59e-08), 1gd2_GH(4.68e-08)
TTACGCGAPubMed1gd2_G(1.67e-04), 1gd2_EF(1.51e-03), 1gd2_GH(1.52e-03)
TTACGTAAPubMed1gd2_G(1.67e-04), 1gd2_EF(6.54e-12), 1gd2_GH(6.70e-12)
AACCTAACPubMed1gd2_G(1.08e-03), 1gd2_EF(2.89e-04), 1gd2_GH(2.96e-04)

Dendrogram of similar interfaces ?

matrix format
  
  ------------------RG------NC----YGAT--CTRG   L      +--------------------------2wt7_B    
                                                      !  
  RG----QGNART--AGQT----FTRG----------------   L      !                          +1gd2_G    
                                                      !                        +-2 
  --------RA----NT----AAVT----STRG----------   L      !             +----------6 +1hjb_A    
                                                      !             !          ! 
  ------------RG------NC----YGAT------RC----   L      !             !          +--4eot_A    
                                                      !       +-----8 
  RC------NC----AAAT----CTRC----------------   L   +-11       !     !             +2wt7_A    
                                                   !  !       !     !           +-1 
  --RA----NA----AAVT----STRG----------------   L   !  !       !     +-----------3 +1h89_A    
                                                   !  !  +----9                 ! 
  ----------NCRT--ATAT----STRG--------------       !  !  !    !                 +-1t2k_D    
                                                   !  !  !    ! 
  ----------RA----NA----AAVT----STRG--------   L   !  !  !    !              +----1nwq_C    
                                                   !  !  !    !              ! 
  ------------NT----ATAT----STRG------------   L -12  +-10    +--------------7   +-1dh3_C    
                                                   !     !                   ! +-4 
  ----------------NC----AT------STRA--------       !     !                   +-5 +-1a02_J    
                                                   !     !                     ! 
  --------NCTT----AT------RG----------------   L   !     !                     +--2dgc_A    
                                                   !     !  
  ----------NT----ATAT------RG--------------   L   !     +------------------------5t01_B    
                                                   !  
  ----RG------NT----ATAT------RG------------   L   +---------------------------5vpe_C    
                                                 

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updated Fri Sep 13 15:37:41 2024