3D-footprint cannot reliably estimate the specificity of histones, as they display few contacts over long stretches of DNA.

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updated Mon Jan 5 13:04:42 2026

structure name	THE NUCLEOSOME CONTAINING HUMAN H3.5
reference	Kurumizaka et al. 'Epigenetics 9 2 2016
source	HOMO SAPIENS
experiment	X-ray (resolution=2.80, R-factor=?)
structural superfamily	Histone-fold;PH domain-like;lambda repressor-like DNA-binding domains;p53-like transcription factors;
reference complex	5gtc_H 5o9g_F 6a5l_d 6a5l_g 6r8y_H 6upk_H 6x0n_f 7d1z_H 7jzv_N 7lyb_G 7nkx_f 7scy_H 7u0g_M 7vdt_B 7xzx_N 8h0v_h 8txv_G 8u14_G 8upf_G
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4z5t_A interface=3,28, phRyrpgtvalreirryqkstellirkLpfqrlvreiaqdfntdlrfqsaavgalqeaseaylvglledtnlcaihakrvtimpkdiqlarrirger > 4z5t_B interface=26, kvlrdniqgitkpairrlarrggvkRisgliyeetrgvlkvflenvirdavtytehakrktvtamdvvyalkrqgrtlygfgg > 4z5t_C interface=29, aktrssraglqfpvgrvhrllrkgnyseRvgagapvylaavleyltaeilelagnaardnkktriiprhlqlairndeelnkllgrvtiaqggvlpniqavllpk > 4z5t_D interface= rkesysiyvykvlkqvhpdtgisskamgImnsfvndiferiageasrlahynkrstitsreiqtavrlllpgelakhavsegtkavtkytsa > 4z5t_E interface=2,3,27, hRYrpgtvalreirryqkstellirkLpfqrlvreiaqdfntdlrfqsaavgalqeaseaylvglledtnlcaihakrvtimpkdiqlarrirger > 4z5t_F interface=22, dniqgitkpairrlarrggvkRisgliyeetrgvlkvflenvirdavtytehakrktvtamdvvyalkrqgrtlygfgg > 4z5t_G interface=28, ktrssraglqfpvgrvhrllrkgnyseRvgagapvylaavleyltaeilelagnaardnkktriiprhlqlairndeelnkllgrvtiaqggvlpniqavllpk > 4z5t_H interface= rkesysiyvykvlkqvhpdtgisskamGimnsfvndiferiageasrlahynkrstitsreiqtavrlllpgelakhavsegtkavtkytsa