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structure nameMUTY N-TERMINAL DOMAIN IN COMPLEX WITH UNDAMAGED DNA
(Adenine DNA glycosylase)
referenceChakravarthy et al. 'J. 292 5007 2017
sourceGeobacillus stearothermophilus
experimentX-ray (resolution=1.81, R-factor=0.169)
structural superfamilyDNA-glycosylase;
sequence familyHhHGPD superfamily base excision DNA r; Helixhairpinhelix motif; Ironsulfur binding domain of endonucle;
redundant complexes5kn9_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureYRACR

Estimated binding specificities ?

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# IC=1.007 IC/col=0.201 n_of_columns=5 specificity:   
A |  19  12  14  24   9
C |  19  60  54  24   9
G |  20  12  14  24  67
T |  38  12  14  24  11
scan!

Dendrogram of similar interfaces ?

matrix format
  
  ----------YG------ACCTRG                                +5kn8_A    
                                          +---------------1 
  --QG--RG--YC------------             +--5               +6u7t_A    
                                       !  ! 
  --QG--QG--YC------------   L   +-----6  +---------------7ef9_A    
                                 !     ! 
  --QTLAHGAT----KT--------       !     +------------------3s6i_A    
                                 ! 
  --NCNANARC--YGRC--------     --8                   +----2xhi_A    
                                 !             +-----3 
  --NG--RG----FGRC--------       !     +-------4     +----4ejy_A    
                                 !     !       ! 
  QGKGLGSGAGSCLTKC--------       +-----7       +----------4b21_A    
                                       ! 
  NGRGTG----LG--LC--------             !                  +6vjw_A    
                                       +------------------2 
  NGRGTG----LG--LCRG------                                +7kz0_A    
                               

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updated Sun Aug 3 09:32:04 2025