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structure nameCRYSTAL STRUCTURE OF WT HMBD4 COMPLEXED WITH T:G MISMATCH DNA
(Methyl-CpG-binding domain protein 4)
referenceJung et al. Biochem.J. 477 1601 2020
sourceHomo sapiens
experimentX-ray (resolution=2.02, R-factor=?)
structural superfamilyDNA-glycosylase;
redundant complexes4evv 4ew0 4ew4
reference complex4ofa_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence

No structural evidence for specific binding to DNA (<4 informative columns)


Dendrogram of similar interfaces ?

matrix format
  
  LTVTQTLTNGRGTG------LC--LCRG--------------YTNT--KT                                          +4ofa_A    
                                                                                   +----------1 
  --------NGRGTG------LG--LCRG----------------------                               !          +7kz0_A    
                                                                           +-------7 
  --------NGRGTG------LG--LCRG----------------------                       !       !   +------4e9f_A    
                                                                    +-----12       +---5 
  ----------QTLAHGAT--------KT----------------------                !      !           +------3s6i_A    
                                                                    !      !  
  --------------------YG----------------------------                !      +------------------5kn8_A    
                                                                 +-16  
  ----------QGCGTA----LC----------------------------             !  !                 +-------1orn_A    
                                                                 !  !            +----6 
  ----------NG--RG------FGRC------------------------             !  +------------8    +-------4ejy_A    
                                                                 !               ! 
  --------AGNG------RCFC----RG------------------RA--             !               +------------3knt_A    
                                                                 !  
  --------HTRT------------------NCSTNARG------------   L      +-17                          +-1k61_B    
                                                              !  !            +-------------3 
  ----------------------------KTIAQCNA----RT--------   L      !  !  +--------10             +-1ig7_A    
                                                              !  !  !         !  
  ------------------------------ITQTNAMG------------   L      !  !  !         +---------------5zjt_E    
                                                              !  !  !  
  ------------------------------VAQTNA--------------   L      !  !  !       +-------------------5hod_A    
                                                              !  !  !       !  
  ------------------------------IA--NA--------------          !  +-15       !                   +4qtr_D    
                                                              !     !    +-13    +--------------2 
  ----------RT------------------NCSTNARG------------   L   +-18     !    !  !  +-9              +1mnm_C    
                                                           !  !     !    !  !  ! ! 
  ------------------------------NCICNARGRG----------   L   !  !     !    !  +-11 +---------------6fqp_B    
                                                           !  !     +---14     !  
  ------------------------------IAQCNAYC------------   L   !  !          !     !            +---3rkq_B    
                                                           !  !          !     +------------4 
  ----------------------------RTVAITNAMCRG----------   L -19  !          !                  +---1yrn_A    
                                                           !  !          !  
  ------------------------------VASGNA--------------   L   !  !          +--------------------3cmy_A    
                                                           !  !  
  ------------------------------VTQTNAMTKTRT--------   L   !  +-----------------------------1jgg_B    
                                                           !  
  ------------------------------IA--NA--------------       +-----------------------------4xrs_G    
                                                         

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updated Fri Sep 13 02:35:38 2024