| structure name | SEPARATION-OF-FUNCTION MUTANTS UNRAVEL THE DUAL REACTION MODE OF HUMAN 8-OXOGUANINE DNA GLYCOSYLASE (N-GLYCOSYLASEDNA LYASE) |
| reference | Forstrom et al. Structure 19 117 2011 |
| source | HOMO SAPIENS |
| experiment | X-ray (resolution=1.55, R-factor=0.231) |
| structural superfamily | DNA-glycosylase;TATA-box binding protein-like; |
| sequence family | 8oxoguanine DNA glycosylase, Nterminal dom; HhHGPD superfamily base excision DNA repair; |
| redundant complexes | 1ebm_A 1fn7_A 1hu0_A 1lwv_A 1lww_A 1lwy_A 1m3q_A 1n39_A 1n3a_A 1n3c_A 1yqk_A 1yql_A 1yqm_A 1yqr_A 2i5w_A 2nob_A 2noe_A 2nof_A 2noh_A 2noi_A 2nol_A 2noz_A 3ih7_A 3ktu_A 6w0m_A 6w0r_A 6w13_A |
| links to other resources | NAKB  PDIdb DNAproDB |
| protein sequence |
No structural evidence for specific binding to DNA (<4 informative columns)
Dendrogram of similar interfaces ?
matrix format--NCNANARC----YGRC-------- +---2xhi_A +----3 --NG--RG------FGRC-------- +-4 +---4ejy_A ! ! --LG------------KG-------- +--------6 +--------3cw7_C ! ! --QTLAHGAT--------KT------ ! +----------3s6i_A +-8 QGKGLGSGAG--SC--LTKC------ ! ! +--------4b21_A ! ! +---5 --QG--QG--YC-------------- L ! ! ! +--------7ef9_A ! +------7 ----------YG--------ACCTRG +----9 ! +5kn8_A ! ! +------------1 --QG--RG--YC-------------- ! ! +6u7t_A ! ! NGRGTG----LG----LC-------- -10 ! +6vjw_A ! +---------------------2 NGRGTG----LG----LCRG------ ! +7kz0_A ! --QGCGTA------------------ +--------------------------1orn_A |
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updated Fri Sep 13 16:47:43 2024