| structure name | GCNF DNA BINDING DOMAIN - OCT4 DR0 COMPLEX (Nuclear receptor subfamily 6 group A member 1) |
| reference | Ortlund et al. 'J. 428 4981 2016 |
| source | Mus musculus |
| experiment | X-ray (resolution=2.10, R-factor=0.218) |
| structural superfamily | Glucocorticoid receptor-like DNA-binding domain; |
| sequence family | Zinc finger, C4 type two domains; |
| multimeric complexes | 5krb_BG |
| links to other resources | NAKB  PDIdb DNAproDB |
| protein sequence | |
| interface signature | EKRPR |
Estimated binding specificities ?
| readout + contact |  |
A | 0 16 24 64 0 0 24 0 80 C | 8 64 24 8 0 0 24 80 8 G | 0 8 24 8 96 96 24 0 8 T | 88 8 24 16 0 0 24 16 0scan! |
Related DNA sequences reported in the literature ?
| site | source | matches (E-value) |
|---|---|---|
| term: GCNF | ||
| AGGTCA | PubMed | 5krb_G(4.54e-05), 5krb_BG(1.13e-04) |
| TCAAGGTCA | PubMed | 5krb_G(2.83e-08), 5krb_BG(3.81e-07) |
| AGGTCAAGGTCA | PubMed | 5krb_G(8.93e-07), 5krb_BG(2.47e-11) |
| TCAAG | PubMed | 5krb_G(3.14e-03), 5krb_BG(5.75e-03) |
Dendrogram of similar interfaces ?
matrix formatCAECKG--KGRG--RTRT L +----1cit_A +-------------4 --EAKG--KTRG------ L ! ! +4umm_A ! +----1 ----KGVG--RG------ L ! +4tnt_B +------5 ----KGVT--RG------ L ! ! +5emc_A ! ! +-2 --ECKGAGKGRG------ L +-6 +----------------3 +1hcq_E ! ! ! --ECKGAG--KTRG---- L ! ! +-4aa6_B --7 ! ----KGVT--RG------ L ! +-------------------------2c7a_B ! --ECKGAG--RG------ L +--------------------------4ond_A |
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updated Mon Jun 29 20:22:08 2026