3D-footprint cannot reliably estimate the specificity of histones, as they display few contacts over long stretches of DNA.


Dendrogram of similar interfaces ?

matrix format
structure nameCRYSTAL STRUCTURE OF THE PFV GAG CBS BOUND TO A MONONUCLEOSOME
(HISTONE H4)
referenceCherepanov et al. 'Proc. 114 5509 2017
sourceXENOPUS LAEVIS
experimentX-ray (resolution=2.80, R-factor=0.209)
structural superfamilyHistone-fold;
sequence familyCore histone H2A/H2B/H3/H4;
multimeric complexes5mlu_ABCDEFGH
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
  
  ----RA--             +-----------------------------6g0l_D    
                     +-7 
  --RG----         +-8 +-----------------------------8ox0_C    
                   ! ! 
  --RG----       +-9 +-----------------------------8jla_C    
                 ! ! 
  --RG----       ! +-----------------------------5x0y_G    
                 !  
  --RA--RA     -10                             +6a5l_g    
                 !      +----------------------1 
  --RG----       !      !                      +8txv_G    
                 !      ! 
  --RT----       +------6                      +8u14_G    
                        !          +-----------2 
  --RA----              !   +------4           +1zla_C    
                        !   !      ! 
  LCRT----              +---5      +-----------8hr1_E    
                            ! 
  --RA----                  !                  +7xsx_a    
                            +------------------3 
  --RT----                                     +8grq_A

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updated Sun Aug 3 09:35:46 2025