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legend  pdf

structure nameCRYSTAL STRUCTURE OF HHV-4 EBNA1 DNA BINDING DOMAIN (PATIENT-DERIVED, NASOPHARYNGEAL CARCINOMA) BOUND TO DNA
(Epstein-Barr nuclear antigen 1)
referenceLieberman et al. Oncotarget 8 7248 2017
sourceHuman herpesvirus 4 (strain B95-8) / Human herpesvirus 4 (strain B95-8)
experimentX-ray (resolution=2.35, R-factor=0.190)
structural superfamilyViral DNA-binding domain;
sequence familyEpstein Barr virus nuclear antigen1, DNAbi;
multimeric complexes1b3t_AB 5t7x_AB 6pw2_ABCD 6pw2_IKL 7u1t_ABCD 8dlf_ABCD
reference complex7u1t_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureWFRKFKTYNR

Estimated binding specificities ?

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# IC=7.430 IC/col=0.929 n_of_columns=8 specificity:   
A |  13   6   6   0  64   0   0   0
C |  16   6  78   0  13  96  96  96
G |  13  82   6   0   6   0   0   0
T |  54   2   6  96  13   0   0   0
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updated Sun Jun 28 13:52:46 2026