interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF SMAD5-MH1 IN COMPLEX WITH A COMPOSITE DNA SEQUENCE
(Mothers against decapentaplegic homolog 5)
referenceWang et al. 'Nucleic 43 9051 2015
sourceMus musculus
experimentX-ray (resolution=3.20, R-factor=0.212)
structural superfamilySMAD MH1 domain;
sequence familyMH1 domain;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureDRQK

Estimated binding specificities ?

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# IC=2.079 IC/col=0.520 n_of_columns=4 specificity:   
A |   4   4   7  11
C |   6  37  71  11
G |  82   4   9  11
T |   4  51   9  63
scan!

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updated Tue Dec 17 02:48:33 2024