interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF SMAD5-MH1 IN COMPLEX WITH A COMPOSITE DNA SEQUENCE
(Mothers against decapentaplegic homolog 5)
referenceWang et al. 'Nucleic 43 9051 2015
sourceMus musculus
experimentX-ray (resolution=3.20, R-factor=0.212)
structural superfamilySMAD MH1 domain;
sequence familyMH1 domain;
multimeric complexes3kmp_AB 5x6g_AB 5x6m_AB 5x6m_EF 6fzs_AB 6fzt_AB
reference complex6fzs_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureDRQK

Estimated binding specificities ?

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# IC=3.142 IC/col=0.786 n_of_columns=4 specificity:   
A |   0  13   0  16
C |   0  13  96  13
G |  96  13   0  13
T |   0  57   0  54
scan!

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updated Mon Dec 18 13:54:12 2023