5xxp_A : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF CBNR_DBD-DNA COMPLEX (LysR-type regulatory protein)
reference	Senda et al. 'FEBS 285 977 2018
source	Cupriavidus necator
experiment	X-ray (resolution=2.55, R-factor=0.222)
structural superfamily	"Winged helix" DNA-binding domain;
sequence family	Bacterial regulatory helixturnhelix protei;
multimeric complexes	5xxp_AB
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5xxp_A interface=28,29,30,31,33,34,52, mefrqlkyfiavaeagnmaaaakrlhvSQPPiTRqmqaleadlgvvllersHrgieltaaghafledarrilelagrsgdrsraaar
interface signature	SQPPTRH

Estimated binding specificities ?

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# IC=6.338 IC/col=0.634 n_of_columns=10

specificity:

A |   7  96  24  24  24   7   7  96   0   7
C |  75   0  24  24  24   9   7   0  96   7
G |   7   0  24  24  24   7   7   0   0  73
T |   7   0  24  24  24  73  75   0   0   9

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Dendrogram of similar interfaces ?

matrix format

  
  --ST----TC----QG------RG------                                   +---7b24_C    
                                         +-------------------------1 
  --DCLT--AG--TTRG------RG------   L   +-2                         +---5h3r_A    
                                       ! ! 
  --------------NASTRGHT--STLT--   L --3 +-----------------------------2c6y_A    
                                       ! 
  STSTQAQG--ST--SART----------KT   L   +-----------------------------5trd_B

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updated Fri Sep 13 20:58:00 2024