interface graph thumbnail
legend  pdf

3D-footprint cannot reliably estimate the specificity of histones, as they display few contacts over long stretches of DNA.


Dendrogram of similar interfaces ?

matrix format
structure nameCENP-A NUCLEOSOME BOUND BY TWO COPIES OF CENP-C(CD) AND TWO COPIES CENP-N(NT)
(HISTONE H3-LIKE CENTROMERIC PROTEIN A)
sourceHOMO SAPIENS
experimentNMR
structural superfamilyHistone-fold;
sequence familyCore histone H2A/H2B/H3/H4;
multimeric complexes6muo_ABCDEFGHM 6mup_ABCDEFGHMN
redundant complexes6muo
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
  
  RG----RT----         +-----------------------------8grq_A    
                     +-9 
  RG--LCRT----       ! +-----------------------------8hr1_E    
                     !  
  --RG--------       !                   +---------8jh2_e    
                     !         +---------4 
  --------RA--     -10         !         +---------6g0l_D    
                     !    +----6 
  ------RA----       !    !    !                   +1zla_C    
                     !    !    !   +---------------3 
  ------RG----       !    !    +---5               +8ox0_C    
                     !    !        ! 
  ------RG----       +----8        +---------------8jla_C    
                          ! 
  ------RA--RA            !                        +6a5l_g    
                          !  +---------------------1 
  ------RG----            !  !                     +8txv_G    
                          +--7 
  ------RT----               !                     +8u14_G    
                             +---------------------2 
  ------RG----                                     +5x0y_G    
                   

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updated Sun Aug 3 12:19:41 2025