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legend  pdf

structure nameCRYSTAL STRUCTURE OF THE DNA BINDING DOMAIN OF HUMAN TRANSCRIPTION FACTOR ERF IN THE REDUCED FORM, IN COMPLEX WITH DOUBLE-STRANDED DNA ACCGGAAGTG
(ETS domain-containing transcription factor ERF)
referenceTsodikov et al. Biochemistry ? ? 2020
sourceHomo sapiens
experimentX-ray (resolution=2.85, R-factor=0.248)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyEtsdomain;
redundant complexes7jsl_L
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureDKRRY

Estimated binding specificities ?

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# IC=4.475 IC/col=0.895 n_of_columns=5 specificity:   
A |  13   0   0  96  54
C |  57   0   0   0  16
G |  13  96  96   0  13
T |  13   0   0   0  13
scan!

Dendrogram of similar interfaces ?

matrix format
  
  SG----------DCKT--RG--RGYA------------   L                                    +3zp5_A    
                                                               +----------------1 
  --------------KT--RG--RGYA------------   L                   !                +3wts_C    
                                                             +-8 
  ------------DCKT--RG--RGYA----KA------   L                 ! !               +5jvt_A    
                                                             ! !     +---------3 
  ------------DCKT--RGATRCYA------------   L                 ! +-----6         +5e8i_D    
                                                      +-----10       ! 
  --NC--------------TT--CT--NGKG--------   L          !      !       +----------7rh2_B    
                                                      !      !  
  ------------DCKT--RGSTRGYC------------   L      +--11      !          +------4uno_A    
                                                  !   !      +----------5 
  ------------------TT--CT--NGKG--------   L      !   !                 +------7oot_B    
                                                  !   !  
  ------------EAKT--RGATRGYA----------RT   L      !   +------------------------3jtg_A    
                                               +-12  
  --------------KT--RGATRGYA------------   L   !  !                            +1bc8_C    
                                               !  !                       +----2 
  ------------DCKT--RG--RGYA------------   L   !  !          +------------4    +1dux_F    
                                               !  !          !            ! 
  --------------STVT----RGQTNT--MT------   L -13  +----------9            +----5d5v_B    
                                               !             ! 
  --------------KT--RGSARGQA----------RA   L   !             !      +----------1yo5_C    
                                               !             +------7 
  ----RGRTKG----------------------YGKC--   L   !                    +----------6lui_A    
                                               !  
  ----------RT--------------------------   L   +-----------------------------5vfx_A    
                                             

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updated Sat Sep 14 02:41:13 2024