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structure nameCRYSTAL STRUCTURE OF TFAM (MITOCHONDRIAL TRANSCRIPTION FACTOR A) BRIDGING TWO NON-SEQUENCE SPECIFIC DNA SUBSTRATES
(Transcription factor A, mitochondrial)
referenceGarcia-Diaz et al. 'Nucleic 50 322 2022
sourceHomo sapiens
experimentX-ray (resolution=2.84, R-factor=0.200)
structural superfamilyHMG-box;
sequence familyHMG high mobility group box;
multimeric complexes6erp_ACF 6erp_BGJ 6erq_ACF 6erq_BGJ 7lbw_AB
reference complex7lbx_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSYLSLTTIMKRYNVFPQL

Estimated binding specificities ?

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# IC=9.785 IC/col=0.362 n_of_columns=27 specificity:   
A |   0   0   0   5  24  24  24  11  24  24  24  24  24  24  24  24  24  24  24  24  66  24  24  90  96   0   6
C |   0  96   0  81  24  24  24  15  24  24  24  24  24  24  24  24  24  24  24  24   5  24  24   6   0   5   5
G |  96   0   0   5  24  24  24  60  24  24  24  24  24  24  24  24  24  24  24  24  15  24  24   0   0  90  80
T |   0   0  96   5  24  24  24  10  24  24  24  24  24  24  24  24  24  24  24  24  10  24  24   0   0   1   5
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updated Tue Dec 17 09:48:32 2024