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structure nameCRYSTAL STRUCTURE OF TFAM (MITOCHONDRIAL TRANSCRIPTION FACTOR A) BRIDGING TWO NON-SEQUENCE SPECIFIC DNA SUBSTRATES
(Transcription factor A, mitochondrial)
referenceGarcia-Diaz et al. 'Nucleic 50 322 2022
sourceHomo sapiens
experimentX-ray (resolution=2.84, R-factor=0.200)
structural superfamilyHMG-box;
sequence familyHMG high mobility group box;
multimeric complexes6erp_ACF 6erp_BGJ 6erq_ACF 6erq_BGJ 7lbw_AB
reference complex7lbx_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSYLSLTTIMKRYNVFPQL

Estimated binding specificities ?

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# IC=13.285 IC/col=0.474 n_of_columns=28 specificity:   
A |   0   0   0   0  24   8   4  24  24  24  24  24  24  24  24  24  24  24  24   4  24  67  24   0  96   0   0  13
C |  96  96   0   0  24  62   6  24  24  24  24  24  24  24  24  24  24  24  24  82  24   8  24   0   0   0  96  14
G |   0   0   0   0  24  13   4  24  24  24  24  24  24  24  24  24  24  24  24   6  24  13  24  96   0  96   0  13
T |   0   0  96  96  24  13  82  24  24  24  24  24  24  24  24  24  24  24  24   4  24   8  24   0   0   0   0  56
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updated Fri Sep 13 04:34:46 2024