interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF TFAM (MITOCHONDRIAL TRANSCRIPTION FACTOR A) IN COMPLEX WITH LSP
(Transcription factor A, mitochondrial)
referenceGarcia-Diaz et al. 'Nucleic 50 322 2022
sourceHomo sapiens
experimentX-ray (resolution=2.70, R-factor=0.210)
structural superfamilyHMG-box;
sequence familyHMG high mobility group box;
multimeric complexes6erp_ACF 6erp_BGJ 6erq_ACF 6erq_BGJ 7lbw_AB
reference complex3tmm_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKSYLSLTTIMKRYNVFPQLK

Estimated binding specificities ?

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# IC=10.250 IC/col=0.641 n_of_columns=16 specificity:   
A |   0   0   0   8  24  24  24  24  24  16  24   0   0   0   0   8
C |   0   0   0   8  24  24  24  24  24  16  24  96   0   0   0  16
G |   0   0  96  72  24  24  24  24  24  56  24   0   0  96   8   8
T |  96  96   0   8  24  24  24  24  24   8  24   0  96   0  88  64
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updated Fri Jan 9 13:26:21 2026