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legend  pdf

structure nameM. TUBERCULOSIS DNA GYRASE CLEAVAGE CORE BOUND TO DNA AND EVYBACTIN
referenceBerger et al. Nat.Chem.Biol. ? ? 2022
experimentX-ray (resolution=3.00, R-factor=0.204)
structural superfamilyType II DNA topoisomerase;
sequence familyDNA gyrase/topoisomerase IV, subunit A;
multimeric complexes5bs8_ABCD 5bta_ABCD 5btc_ABCD 5btd_ABCD 5btf_ABCD 5btg_ABCD 5bti_ABCD 5btl_ABCD 5btn_ABCD 7ugw_ABCD
reference complex5bs8_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureYSI

Estimated binding specificities ?

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# IC=2.828 IC/col=0.218 n_of_columns=13 specificity:   
A |   7   0  24  24  24  24  24  24  24  24  24  16   4
C |  74   0  24  24  24  24  24  24  24  24  24  48   4
G |   8  96  24  24  24  24  24  24  24  24  24  16  81
T |   7   0  24  24  24  24  24  24  24  24  24  16   7
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updated Fri Sep 13 08:07:38 2024