8cy2_A : 3D-footprint complex

structure name	CAMA ADENINE METHYLTRANSFERASE COMPLEXED TO COGNATE SUBSTRATE DNA AND INHIBITOR APNEA (COMPOUND 9) (Site-specific DNA-methyltransferase adenine-specific)
reference	Horton et al. J.Med.Chem. 66 934 2023
source	Clostridioides difficile
experiment	X-ray (resolution=2.81, R-factor=0.172)
structural superfamily	S-adenosyl-L-methionine-dependent methyltransferases;
sequence family	N6 DNA Methylase 1743;
multimeric complexes	8cxs_AB 8cxt_AB 8cxu_AB 8cxv_AB 8cxw_AB 8cxx_AB 8cxy_AB 8cxz_AB 8cy0_AB 8cy1_AB 8cy2_AB 8cy3_AB 8cy4_AB 8cy5_AB 8fs1_AB 8fs2_AB
reference complex	8cxy_C
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8cy2_A interface=3,132,135,138,139,159,160,188,220,223,225,313,316,346,392,393,398,405,406,408,422,423,439,440,441,443,480,481,484,488, giYytpkiivdyivkktlknhdiiknpyprildiscgcgnfllevydilydlfeeniyelkkkydenywtvdnihrhilnyciygadidekaisilkdsltnkkesdikinlfccdslkkkwrykfdyivgNppYigHKklekkykkfllekysevykDKadlyfcfykkiidilkqggigsvitprYfleslsgkdlreyiksnvnvqeivdflganiFknIgVssciltfdkkktketyidvfkiknedicinkfetleellksskfehfninqrllsdewilvnkddetfynkiqekckyslediaisfQgiItgcdkafilskddvklnlvddkflkcwikSkninkyivdkseyrliysndidnentnkrildeiiglyktklenrREcksgIrkwyelQWgReklfferkkimypYKsnenrfaidydnnfsSADvYsffikeeyldkfsyeylvgilnssvydkyfkitakkMSknIydyYpnkvmkirifrdnnyeeienlskqiisillnksidkgkveklqikmdnlimdslgi
interface signature	YNYHKDKYFIVQISREIQWRYKSADYMSIY

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# IC=9.095 IC/col=1.137 n_of_columns=8

A |  16   0   0   0   0   0   0  88
C |  45   0   0   0   0   0   0   2
G |  16   0   0   0   0   0  96   4
T |  19  96  96  96  96  96   0   2

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updated Mon Jun 29 06:33:10 2026