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structure nameCAMA ADENINE METHYLTRANSFERASE COMPLEXED TO COGNATE SUBSTRATE DNA AND INHIBITOR 11B (YD907)
(Site-specific DNA-methyltransferase adenine-specific)
referenceHorton et al. 'Acs 18 734 2023
sourceClostridioides difficile
experimentX-ray (resolution=2.59, R-factor=0.174)
structural superfamilyS-adenosyl-L-methionine-dependent methyltransferases;
sequence familyN6 DNA Methylase 1794;
multimeric complexes8cxs_AB 8cxt_AB 8cxu_AB 8cxv_AB 8cxw_AB 8cxx_AB 8cxy_AB 8cxz_AB 8cy0_AB 8cy1_AB 8cy2_AB 8cy3_AB 8cy4_AB 8cy5_AB 8fs1_AB 8fs2_AB
reference complex8cxy_C
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureYNYHKDKYFNIVQISREIQWRYKSADYMSIY

Estimated binding specificities ?

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# IC=9.174 IC/col=1.147 n_of_columns=8 specificity:   
A |  14   0   0   0   0   0   0  88
C |  52   0   0   0   0   0   0   4
G |  16   0   0   0   0   0  96   2
T |  14  96  96  96  96  96   0   2
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updated Mon Jun 29 07:40:51 2026