structure name | DNA BINDING DOMAIN OF HNF-1A BOUND TO P2-HNF4A PROMOTER DNA VARIANT (P2 -181G>A) (Hepatocyte nuclear factor 1-alpha) |
reference | Myllykoski et al. 'JCI 9 ? 2024 |
source | Homo sapiens |
experiment | X-ray (resolution=2.80, R-factor=0.237) |
structural superfamily | lambda repressor-like DNA-binding domains;Homeodomain-like; |
sequence family | Hepatocyte nuclear factor 1 HNF1, N termi; Homeobox domain 08; |
multimeric complexes | 1ic8_AB 8pi7_AB 8pi8_AB 8pi9_AB 8pia_AB |
reference complex | 8pi8_B |
links to other resources | NAKB PDIdb DNAproDB |
protein sequence | |
interface signature | NQSHSQTRYNK |
Estimated binding specificities ?
readout + contact |
A | 6 24 3 24 6 24 84 84 24 3 92 3 3 96 C | 3 24 87 24 3 24 6 3 24 3 1 3 3 0 G | 3 24 3 24 3 24 3 6 24 87 0 84 6 0 T | 84 24 3 24 84 24 3 3 24 3 3 6 84 0scan! |
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updated Tue Dec 17 19:03:08 2024