interface graph thumbnail
legend  pdf

structure nameCOSR DNA BOUND FORM II
(DNA-binding response regulator)
referenceMbio 15 e0343023 2024 X-RAY DIFFRACTION
sourceCampylobacter jejuni
experimentX-ray (resolution=2.21, R-factor=0.254)
structural superfamilyCheY-like;
sequence familyTranscriptional regulatory protein, C te; Response regulator receiver domain;
multimeric complexes8uvk_AB 8uvx_AB
redundant complexes8uvx_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureNVEVNR

Estimated binding specificities ?

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# IC=5.165 IC/col=0.646 n_of_columns=8 specificity:   
A |  52  10  24  24  17   0   0  96
C |  10   0  24  24  52   0   0   0
G |  17   8  24  24   8   0   0   0
T |  17  78  24  24  19  96  96   0
scan!

Dendrogram of similar interfaces ?

matrix format
  
  --RG--DTVTSTRG--------WT----   L          +------------------------6lxn_A    
                                            ! 
  ----------YG----------------         +----3                    +---3eyi_B    
                                       !    !      +-------------1 
  --------RCYG--------KT------         !    +------2             +---2acj_B    
                                     +-4           ! 
  TTKATTQTTG----LTRTKA----FTYT   L   ! !           +-----------------2p7c_B    
                                   --5 ! 
  --RG--DTVTST--RG------RC----   L   ! +-----------------------------4nhj_A    
                                     ! 
  --------VTKGNAKA------------   L   +-----------------------------2lkx_A    
                                   

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updated Sun Jan 11 01:35:42 2026