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legend  pdf

structure nameINTERFERON REGULATORY FACTOR 1 (IRF-1) COMPLEX WITH DNA
(PROTEIN INTERFERON REGULATORY FACTOR 1)
referenceEscalante et al.
sourceMus musculus
experimentX-ray (resolution=3.00, R-factor=0.242)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyInterferon regulatory factor transcription f;
multimeric complexes1if1_AB
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureHNRCNS

Estimated binding specificities ?

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# IC=4.501 IC/col=0.750 n_of_columns=6 specificity:   
A |  20  19   3  19   0  96
C |  68  20   5  13  96   0
G |   3   3   3  20   0   0
T |   5  54  85  44   0   0
scan!

Related DNA sequences reported in the literature ?


sitesourcematches (E-value)
term: IRF-1
GAAANNPubMed1if1_B(1.18e-03)
GAAAGTPubMed1if1_B(9.73e-07), 1if1_AB(1.42e-03)
GTAAAGAAAGTPubMed1if1_B(1.18e-04)
AAAGGAPubMed1if1_B(1.20e-03)
GAAAGPubMed1if1_B(1.34e-07)

Dendrogram of similar interfaces ?

matrix format
  
  HTLT------RGNT--RGSTAT--RA--   L       +-----------------------------2o6g_G    
                                       +-2 
  ------QCKT--RGAT--RGNT------   L   +-3 +-----------------------------8smh_F    
                                     ! ! 
  ----------NAST--RTHT--STLT--   L --4 +-----------------------------4lg0_A    
                                     ! 
  ----DCKT--RGST----RGYA------   L   !                            +4bnc_A    
                                     +----------------------------1 
  ----DCKT--RG------RGYA----KA   L                                +5jvt_A

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updated Sat Jan 10 04:40:11 2026