1l3l_A : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF A BACTERIAL QUORUM-SENSING TRANSCRIPTION FACTOR COMPLEXED WITH PHEROMONE AND DNA (Transcriptional activator protein traR)
reference	Molyneaux et al. Nature 417 971 2002
source	Agrobacterium tumefaciens
experiment	X-ray (resolution=1.66, R-factor=?)
structural superfamily	Pheromone-binding domain of LuxR-like quorum-sensing transcription factors;C-terminal effector domain of the bipartite response regulators;
sequence family	Autoinducer binding domain; Bacterial regulatory proteins, luxR fami;
multimeric complexes	1h0m_AB 1h0m_CD 1l3l_AC 1l3l_BD
redundant complexes	1h0m_C
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1l3l_A interface=190,201,202,205,206,209,210, qhwldkltdlaaiegdecilktgladiadhfgftgyaylhiqhrhitavtnyhrqwqstyfdkkfealdpvvkrarsrkhiftwsgeherptlskderafydhasdfgirsgitipiktangfmsmftmasdkpvidldreidavaaaatigqiharisflrttptaedaawldpkeatylrwiavgktMeeiadvegvkYNsvRVklREamkrfdvrskahltalairrkli
interface signature	MYNRVRE

Estimated binding specificities ?

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# IC=5.128 IC/col=0.855 n_of_columns=6

specificity:

A |   8   0   0  96  56  48
C |  16   0  96   0  24  16
G |   0  96   0   0   8  24
T |  72   0   0   0   8   8

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Dendrogram of similar interfaces ?

matrix format

  
  --YTNT--RGVT--RTET   L          +-------------------1l3l_A    
                             +----1 
  TC--KTTCKGTCHTST--   L   +-2    +-------------------7ve5_B    
                           ! ! 
  ----KGTCKGTCHT----   L --3 +------------------------4wuh_B    
                           ! 
  ----SCTAKTVCHTKG--   L   +--------------------------1je8_F

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updated Fri Sep 13 15:47:00 2024