interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF E. FAECALIS DNA BINDING DOMAIN LIAR WILD TYPE COMPLEXED WITH 22BP DNA
(Response regulator receiver domain protein)
referenceDavlieva et al. 'Nucleic 43 4758 2015
sourceEnterococcus faecalis S613
experimentX-ray (resolution=2.29, R-factor=0.219)
structural superfamilyC-terminal effector domain of the bipartite response regulators;
sequence familyBacterial regulatory proteins, luxR fami; Sigma70, region 4;
multimeric complexes4wu4_AB 4wul_AB
redundant complexes4wu4_A 4wul_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKTKTH

Estimated binding specificities ?

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# IC=5.849 IC/col=0.836 n_of_columns=7 specificity:   
A |   0   0   0  13  24   0  13
C |   0  96   0  13  24  96  13
G |   0   0  96  13  24   0  13
T |  96   0   0  57  24   0  57
scan!

Dendrogram of similar interfaces ?

matrix format
  
  --KGTG--KANGYAST--   L       +-----------------------------1zlk_A    
                             +-1 
  ----ST--TAQC--ST--       +-2 +-----------------------------8b4b_W    
                           ! ! 
  NTHG--RT--YTPT----   L --3 +-----------------------------6qil_A    
                           ! 
  --RGTC--DCVA--RGRC   L   +-----------------------------8hih_Q    
                         

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updated Sun Aug 3 08:33:54 2025