| structure name | CRYSTAL STRUCTURE OF THE HUMAN FOXO3A-DBD BOUND TO DNA (FORKHEAD BOX PROTEIN O3A) |
| reference | Huang et al. 'Nucleic 35 6984 2007 |
| source | HOMO SAPIENS |
| experiment | X-ray (resolution=2.70, R-factor=0.242) |
| structural superfamily | "Winged helix" DNA-binding domain; |
| sequence family | Fork head domain; |
| links to other resources | NAKB  PDIdb DNAproDB |
| protein sequence | |
| interface signature | NSRHSR |
Estimated binding specificities ?
readout + contact |  |
A | 4 78 96 38 7 56 C | 2 6 0 19 75 13 G | 2 6 0 19 7 14 T | 88 6 0 20 7 13scan! |
Related DNA sequences reported in the literature ?
| site | source | matches (E-value) |
|---|---|---|
| term: FOXO3A | ||
| GTAAACA | PubMed | 2uzk_A(6.32e-06) |
| TTGTTTCA | PubMed | 2uzk_A(6.38e-03) |
Dendrogram of similar interfaces ?
matrix format----ST------NASTRTHT--ST---------- L +---3l2c_A +-----1 ------------NASTRGHT--STLT-------- L +------2 +---7cby_C ! ! --------STRTSTHG------------RA---- L +---3 +---------3zpl_B ! ! --LA--NTTTETYTRG------------------ L --4 +----------------1f4k_B ! TT------KATTQTTG--LTRT----KA--FTYT L +--------------------2p7c_B |
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updated Sun Aug 3 06:33:16 2025