3D-footprint cannot reliably estimate the specificity of histones, as they display few contacts over long stretches of DNA.

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updated Mon Sep 9 16:45:32 2024

structure name	CRYSTAL STRUCTURE OF HUMAN NUCLEOSOME CORE PARTICLE CONTAINING H3K122Q MUTATION
reference	Kurumizaka et al. Biochemistry 50 7822 2011
source	HOMO SAPIENS
experiment	X-ray (resolution=3.49, R-factor=?)
structural superfamily	Histone-fold;P-loop containing nucleoside triphosphate hydrolases;Chromo domain-like;Homeodomain-like;PH domain-like;lambda repressor-like DNA-binding domains;p53-like transcription factors;Nucleic acid-binding proteins;
reference complex	5gtc_H 5o9g_E 5o9g_F 5o9g_G 5z3u_A 6a5l_d 6buz_H 6c0w_H 6ftx_B 6g0l_M 6iro_A 6nqa_A 6pww_K 6r25_E 6r8y_H 6see_H 6t7a_H 6upk_H 6x0n_f 6x59_H 6y5d_H 6yov_C 7at8_D 7d1z_H 7e8d_H 7eg6_A 7egp_S 7jzv_N 7k5x_H 7k60_H 7k63_H 7nkx_a 7nkx_f 7otq_E 7pet_H 7scy_H 7u0g_M 7unc_a 7und_e 7vdt_B 7xcr_F 7xzx_N 7xzz_N 7zs9_e 8a3y_a 8aag_A 8atf_Q 8bvw_e 8byq_e 8ceo_r 8cww_A 8g57_E 8h0v_h 8he5_a 8jh2_e 8jhf_A 8siy_G 8xgc_4
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 3azh_A interface=2,3,28,46, pHRyrpgtvalreirryqkstellirkLpfqrlvreiaqdfktdlRfqssavmalqeaceaylvglfedtnlcaihakrvtimpqdiqlarrirger > 3azh_B interface=21, niqgitkpairrlarrggvkRisgliyeetrgvlkvflenvirdavtytehakrktvtamdvvyalkrqgrtlygfgg > 3azh_C interface=30, kaktrssraglqfpvgrvhrllrkgnyseRvgagapvylaavleyltaeilelagnaardnkktriiprhlqlairndeelnkllgrvtiaqggvlpniqavllpk > 3azh_D interface=2,10, kRsrkesysIyvykvlkqvhpdtgisskamgimnsfvndiferiageasrlahynkrstitsreiqtavrlllpgelakhavsegtkavtkytsa > 3azh_E interface=1,3,4,5,29, KpHRYrpgtvalreirryqkstellirkLpfqrlvreiaqdfktdlrfqssavmalqeaceaylvglfedtnlcaihakrvtimpqdiqlarrirgera > 3azh_F interface=15,28, hrkvlrdniqgitkPairrlarrggvkRisgliyeetrgvlkvflenvirdavtytehakrktvtamdvvyalkrqgrtlygfg > 3azh_G interface= ktrssraglqfpvgRvhrllrkgnyseRvgagapvylaavleyltaeilelagnaardnkktriiprhlqlairndeelnkllgrvtiaqggvlpniqavllpk > 3azh_H interface=1, Rkesysiyvykvlkqvhpdtgisskamgimnsfvndiferiageasrlahynkrstitsreiqtavrlllpgelakhavsegtkavtkytsa