interface graph thumbnail
legend  pdf

structure nameI-MSOI RE-DESIGNED FOR ALTERED DNA CLEAVAGE SPECIFICITY (-7C)
(Site-specific DNA endonuclease I-MsoI)
referenceStoddard et al. 'Nucleic 38 5601 2010
sourceMonomastix sp.
experimentX-ray (resolution=2.90, R-factor=0.252)
structural superfamilyHoming endonucleases;
sequence familyLAGLIDADG endonuclease;
multimeric complexes1m5x_AB 2fld_AB 3ko2_AB 3ko2_FG 3mip_AB 3mis_AB
reference complex2fld_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSYRIRDEIRRDIW

Estimated binding specificities ?

readout + contactlogo
# IC=9.764 IC/col=1.085 n_of_columns=9 specificity:   
A |   0  96  96  13   0   0   0   0  16
C |   0   0   0  54   0   0   0  96  13
G |  96   0   0  16   0  96   0   0  13
T |   0   0   0  13  96   0  96   0  54
scan!

home
updated Sat Aug 2 04:13:54 2025