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structure nameDNA POLYMERASE ETA IN COMPLEX WITH A CIS-SYN THYMIDINE DIMER
(DNA polymerase eta)
referenceSilverstein et al. Nature 465 1039 2010
sourceSaccharomyces cerevisiae
experimentX-ray (resolution=1.76, R-factor=0.165)
structural superfamilyDNA/RNA polymerases;Lesion bypass DNA polymerase Y-family, little finger domain;
sequence familyimpB/mucB/samB family;
redundant complexes2r8j_B 2r8k_A 2wtf_A 2xgp_B 2xgq_A 3mfh_A 3oha_A 3ohb_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence

No structural evidence for specific binding to DNA (<4 informative columns)


Dendrogram of similar interfaces ?

matrix format
  
  ----------------------------------MANG----------YARC--ST--------                       +-------3mfi_A    
                                                                              +----------6 
  --YG----------------------------------EG------RA------QA--------       +----8          +-------3osn_A    
                                                                         !    ! 
  ------IT----------------------------ST--PATA------------RC------       !    +------------------7m7n_A    
                                                                         !  
  ----AG--------PCIAKAQA--------KC----YC----------LCST--------RC--       !                           +4f4y_B    
                                                                         !                         +-1 
  ----AC----AG--------------------ST--YG------RG--LC----------RCKT       !                       +-2 +4f4z_A    
                                                                         !                       ! ! 
  ----AGAG------PC--------------------IC--------HALCST--------RGRG     -10                     +-3 +4f4w_A    
                                                                         !                     ! ! 
  ----VASA----AAPT--MT----------------EG------RT--FT--------RT----       !       +-------------5 +5yuy_A    
                                                                         !       !             ! 
  FCYC----TTAT----------SCICDCEC--ST--------------------------RCRT       !       !             ! +4tqr_A    
                                                                         ! +-----7             +-4 
  ----EG--------FG----------------------ET------------------------       ! !     !               +3gqc_A    
                                                                         +-9     ! 
  ----MA--------PAFAIA----------------EC----------FTTG------------         !     +---------------7nv0_A    
                                                                           ! 
  ----MASA----AAPC--IC----------------EG--------------TG--------RG         +---------------------2oh2_B    
                                                                       

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updated Fri Sep 13 17:25:17 2024