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structure nameI-MSOI RE-DESIGNED FOR ALTERED DNA CLEAVAGE SPECIFICITY (-8GCG)
(MSO-8G)
referenceStoddard et al. 'Nucleic 38 5601 2010
sourceSYNTHETIC CONSTRUCT
experimentX-ray (resolution=2.40, R-factor=0.232)
structural superfamilyHoming endonucleases;
sequence familyLAGLIDADG endonuclease;
multimeric complexes1m5x_AB 2fld_AB 3ko2_AB 3ko2_FG 3mip_AB 3mis_AB
reference complex2fld_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSYRERDYQRIRRDIRY

Estimated binding specificities ?

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# IC=10.068 IC/col=1.007 n_of_columns=10 specificity:   
A |  76   0  76   0   0   0   0   7   8   6
C |   6   0   6  96  96   0  96   6  76  76
G |   6  96   8   0   0  96   0   0   6   6
T |   8   0   6   0   0   0   0  83   6   8
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updated Thu Sep 12 17:43:03 2024