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structure nameI-MSOI RE-DESIGNED FOR ALTERED DNA CLEAVAGE SPECIFICITY (-8GCG)
(MSO-8G)
referenceStoddard et al. 'Nucleic 38 5601 2010
sourceSYNTHETIC CONSTRUCT
experimentX-ray (resolution=2.40, R-factor=0.232)
structural superfamilyHoming endonucleases;
sequence familyLAGLIDADG endonuclease;
multimeric complexes1m5x_AB 2fld_AB 3ko2_AB 3ko2_FG 3mip_AB 3mis_AB
reference complex2fld_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSYRERDYQRIRRDIRY

Estimated binding specificities ?

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# IC=10.143 IC/col=1.014 n_of_columns=10 specificity:   
A |   6   6  84   0   0   0   0   8   0   8
C |   6   6   0   0  96   0   0   6  96   6
G |  76  78   6  96   0  96  96   6   0   6
T |   8   6   6   0   0   0   0  76   0  76
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updated Sat Aug 2 04:28:51 2025