3mis_A : 3D-footprint complex

structure name	I-MSOI RE-DESIGNED FOR ALTERED DNA CLEAVAGE SPECIFICITY (-8G) (MSO-8G)
reference	Stoddard et al. 'Nucleic 38 5601 2010
source	SYNTHETIC CONSTRUCT
experiment	X-ray (resolution=2.30, R-factor=0.249)
structural superfamily	Homing endonucleases;
sequence family	LAGLIDADG endonuclease;
multimeric complexes	1m5x_AB 2fld_AB 3ko2_AB 3ko2_FG 3mip_AB 3mis_AB
reference complex	2fld_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 3mis_A interface=19,21,23,25,27,29,30,36,38,44,67,70,72,74,80, tlqpteaayiagfldgdgSiYaKlEpRpDYkdikyQvRlaisfIqrkdkfpylqdiydqlgkrgnlRkdRgDgIadytiYgsthlsiilpdlvpylrikkkqanrilhiinlypqaqknpskfldlvkivddvqnlnkradelkstnydrlleeflkagki
interface signature	SYKERDYQRIRRDIY

Estimated binding specificities ?

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# IC=12.245 IC/col=1.113 n_of_columns=11

specificity:

A |  12  12  96   0   0   0   0   0   0   0  12
C |  60   0   0  96   0   0  96  96   0   0  60
G |  12  84   0   0  96   0   0   0   0  96  12
T |  12   0   0   0   0  96   0   0  96   0  12

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updated Thu Sep 12 17:43:13 2024