interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF DNA-GLYCOSYLASE BOUND TO DNA CONTAINING THYMINE GLYCOL
(Probable formamidopyrimidine-DNA glycosylase)
referenceWallace et al.
sourceAcanthamoeba polyphaga mimivirus
experimentX-ray (resolution=2.00, R-factor=0.201)
structural superfamilyN-terminal domain of MutM-like DNA repair proteins;S13-like H2TH domain;
sequence familyFormamidopyrimidineDNA glycosylase N; FormamidopyrimidineDNA glycosylase H2;
redundant complexes3a46_A 3vk7_B 4nrw_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRLMRFSKNR

Estimated binding specificities ?

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# IC=5.582 IC/col=0.797 n_of_columns=7 specificity:   
A |  12  60   0  84   0  24   0
C |  12  12   0  12  96  24   0
G |  12  12  96   0   0  24   0
T |  60  12   0   0   0  24  96
scan!

Dendrogram of similar interfaces ?

matrix format
  
  --LGMTRCFCSAKANGRT   L          +-------3vk8_B    
                           +------3 
  RTMT--RCFA------RT       !      !   +---6fl1_A    
                           !      +---1 
  --MG--RCFC------RT   L --4          +---6tc9_A    
                           ! 
  --MGITRCFG--------   L   !       +-----5itu_A    
                           +-------2 
  --MGITRCFG--------               +-----6lwd_G    
                         

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updated Sat Jan 10 06:38:06 2026