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structure nameCRYSTAL STRUCTURE OF RUNX1 AND ETS1 BOUND TO TCR ALPHA PROMOTER (CRYSTAL FORM 1)
(RUNT-RELATED TRANSCRIPTION FACTOR 1)
referenceLeukemia 28 2040 2014
sourceMUS MUSCULUS
experimentX-ray (resolution=2.50, R-factor=0.225)
structural superfamilyp53-like transcription factors;
sequence familyRunt domain;
multimeric complexes4l0y_AB 4l0z_AB
redundant complexes4l0z
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRRVDRR

Estimated binding specificities ?

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# IC=7.082 IC/col=0.885 n_of_columns=8 specificity:   
A |   8   0   4   0   0   8   8   4
C |   8   0   4   0   0  48   8   8
G |   8  96   4  96  96   8   8   0
T |  72   0  84   0   0  32  72  84
scan!

Dendrogram of similar interfaces ?

matrix format
  
  RGRTVCDC--RG   L                                +4l0y_A    
                                                +-1 
  RGRTVCDC--RG   L                            +-2 +4l18_E    
                                              ! ! 
  RGRTVCDC--RG   L        +-------------------3 +3wu1_A    
                          !                   ! 
  RGRAVCDC--RT   L      +-4                   +-6vg8_D    
                        ! ! 
  ----------RG       +--5 +---------------------7b4n_A    
                     !  ! 
  ----ATCT--RG     --6  +-----------------------3qyn_C    
                     ! 
  ----VTHGNTQT   L   +--------------------------4y5w_B

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updated Fri Sep 13 18:27:29 2024