4mhg_A : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF ETV6 BOUND TO A SPECIFIC DNA SEQUENCE (Transcription factor ETV6)
reference	Coyne III et al. J.Mol.Biol. 426 1390 2014
source	Mus musculus
experiment	X-ray (resolution=2.20, R-factor=0.177)
structural superfamily	"Winged helix" DNA-binding domain;
sequence family	Etsdomain;
redundant complexes	8e66_F 8e67_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4mhg_A interface=54,55,57,58,59,61,62,76, rllwdyvyqllsdsryenfirwedkeskifrivdpnglarlwgnhknrtnmtyEKmSRAlRHyyklniirkepgqRllfrfmktpdeims
interface signature	EKSRARHR

Estimated binding specificities ?

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# IC=7.008 IC/col=0.876 n_of_columns=8

specificity:

A |  54  24   0   0   0   0  68  96
C |  13  24  96  83   0   0   2   0
G |  13  24   0   0  96  96  13   0
T |  16  24   0  13   0   0  13   0

scan!

Dendrogram of similar interfaces ?

matrix format

  
  DCKT--RG----RGYAKA   L                                +5jvt_A    
                                   +--------------------1 
  DCKT--RGST--RGYA--   L   +-------2                    +4bnc_A    
                           !       ! 
  ----RGNT--RGSTAT--   L --3       +---------------------2o6g_G    
                           ! 
  QCKT--RGAT--RGNT--   L   +-----------------------------8smh_F

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updated Sat Jan 10 07:16:52 2026