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structure nameCRYSTAL STRUCTURE OF A PRE-CLEAVAGE MOS1 TRANSPOSOSOME
(Mariner Mos1 transposase)
reference'Nucleic 43 2424 2015
sourceDrosophila mauritiana
experimentX-ray (resolution=3.09, R-factor=0.230)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyTransposase;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKERHKPSQQAS

Estimated binding specificities ?

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# IC=13.991 IC/col=0.736 n_of_columns=19 specificity:   
A |  80   6   7  96   0  96  24  24   4   0  66  13  24  24  24   0   0   0  92
C |   6  69   3   0  96   0  24  24   3  83  12   9  24  24  24   0   0   0   0
G |   3   9  86   0   0   0  24  24   3  12   9   9  24  24  24   0  96   0   1
T |   7  12   0   0   0   0  24  24  86   1   9  65  24  24  24  96   0  96   3
scan!

Dendrogram of similar interfaces ?

matrix format
  
  ------KGECRG--------HCKTPTSTQAQGATSA--RAFG--------------------------------   L                    +-------------------4u7b_B    
                                                                                              +-----3 
  HGSGRGHGRT----------RA--RTSTKGRGTTLGNT------------------------------------   L              !     +-------------------1u78_A    
                                                                                              ! 
  ------------------------------------------------------QG--------ECSCKG----               +--5                        +6vdk_A    
                                                                                           !  ! +----------------------2 
  --------------------------------------------QT------PAQG--AG----ECRGQG----   L           !  ! !                      ! +7u32_A    
                                                                                           !  +-4                      +-1 
  ------------------------------------------------------QG--------ECSGHCQT--             +-6    !                        +6rwm_A    
                                                                                         ! !    ! 
  ------------------------------------------WA----TA----QG--AG----ECRTRC----   L         ! !    +-----------------------7jn3_E    
                                                                                       +-7 ! 
  ----------------------------------------------------RT--NA--FTIA--------RA   L       ! ! +----------------------------6edb_B    
                                                                                     +-8 ! 
  ----------------------------------------------RT--SC----------------------         ! ! +----------------------------4n41_B    
                                                                                   +-9 ! 
  ----------------------------------------------------RC--NG--FTMA--------RT   L   ! ! +----------------------------6t90_L    
                                                                                 -10 ! 
  --------FTYAQTNAATRG------------------------------------------------------   L   ! +----------------------------6ryd_F    
                                                                                   !  
  ----------------------------------------------------RC--NT--FTMA--------RA   L   +----------------------------4euw_A    
                                                                                 

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updated Fri Sep 13 18:47:28 2024