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legend  pdf

structure nameWUS-HD BOUND TO TGAA DNA
(Protein WUSCHEL)
referenceSloan et al. 'Nat 11 2223 2020
sourceArabidopsis thaliana
experimentX-ray (resolution=1.57, R-factor=0.189)
structural superfamilyHomeodomain-like;
sequence familyHomeobox domain;
multimeric complexes6ryd_EF 6ryi_AB 6ryi_DE 6ryl_ABC 6ryl_DE
redundant complexes6ryi_D 6ryl_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRFYQNAR

Estimated binding specificities ?

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# IC=6.216 IC/col=0.888 n_of_columns=7 specificity:   
A |  16  44   1   0   0  96   0
C |  51   0   7   0  96   0   9
G |  22  22   0   0   0   0  14
T |   7  30  88  96   0   0  73
scan!

Dendrogram of similar interfaces ?

matrix format
  
  --------------FTYA--QTNA--ATRG   L                                       +6ryd_F    
                                                           +---------------3 
  ----------------YA--QTNA--AARG   L                  +----7               +6wig_A    
                                                      !    ! 
  HTRA------------NC--ATAT--AT--   L               +-10    +---------------1le8_B    
                                                   !  !  
  --------------LA--RTET--QT----   L            +-11  +--------------------7m5w_A    
                                                !  !  
  ------NT----------------------             +-12  +----------------------7tve_F    
                                             !  !  
  --RT------------NC--STNA--RG--   L         !  !                      +1mnm_C    
                                             !  +----------------------4 
  ----------------NT----NA--IARG   L         !                         +1b72_B    
                                             !  
  ----------------NC--ICNA--RGRG   L         !                         +4xrm_B    
                                          +-13         +---------------1 
  ----------------NT----NA--ITRG          !  !         !               +5zjt_B    
                                          !  !       +-6 
  ----------------VA--QTNA------   L      !  !       ! !           +---5hod_A    
                                          !  !     +-8 +-----------5 
  --------------RCVA--CTNA--QA--   L      !  !     ! !             +---7xrc_C    
                                       +-14  !     ! ! 
  --------------RTVA--ITNA--MCRG   L   !  !  +-----9 +-----------------1yrn_A    
                                       !  !        ! 
  ----------------VT--KGNA----KA   L   !  !        !                  +2lkx_A    
                                     -15  !        +------------------2 
  ----------------IA--QCNA--YA--   L   !  !                           +1nk2_P    
                                       !  !  
  --------RCET----SA--QAKT------   L   !  +-------------------------6qec_A    
                                       !  
  ----DT--RGRCTT--KT------------   L   +---------------------------2o9l_A    
                                     

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updated Wed Dec 18 05:39:58 2024