5cbz_E : 3D-footprint complex

structure name	ANCMR DNA BINDING DOMAIN - (+)GRE COMPLEX (ANCMR DNA BINDING DOMAIN)
reference	Ortlund et al. Proc.Natl.Acad.Sci.USA 113 326 2016
source	UNIDENTIFIED
experiment	X-ray (resolution=2.20, R-factor=0.197)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
sequence family	Zinc finger, C4 type two domains;
multimeric complexes	5cbz_AB 5cbz_EF
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5cbz_E interface=27,28,32, ppskvclvcgdeasgchygvltcgscKVffkRavegqhnylcagrndciidkirrkncpacrlrkclqagmnlgar
interface signature	KVR

Estimated binding specificities ?

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# IC=3.101 IC/col=0.620 n_of_columns=5

specificity:

A |  13  24  54   0  96
C |  13  24  16  96   0
G |  54  24  13   0   0
T |  16  24  13   0   0

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Dendrogram of similar interfaces ?

matrix format

  
  ----KGVT--RG--   L     +-----------------------------2c7a_B    
                       +-4 
  --EAKG--KTRG--   L   ! +-----------------------------4umm_A    
                       ! 
  CAECKG--KGRG--   L --5                       +-----1cit_A    
                       !     +-----------------2 
  --ECKGAG--RG--   L   !     !                 +-----4ond_A    
                       +-----3 
  --ECKGAGKGRG--   L         !                      +1hcq_E    
                             +----------------------1 
  --ECKGAGKT--RG   L                                +4aa6_B

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updated Sat Jan 10 07:56:09 2026