interface graph thumbnail
legend  pdf

structure nameANCMR DNA BINDING DOMAIN - (+)GRE COMPLEX
(ANCMR DNA BINDING DOMAIN)
referenceOrtlund et al. Proc.Natl.Acad.Sci.USA 113 326 2016
sourceUNIDENTIFIED
experimentX-ray (resolution=2.20, R-factor=0.197)
structural superfamilyGlucocorticoid receptor-like DNA-binding domain;
sequence familyZinc finger, C4 type two domains;
multimeric complexes5cbz_AB 5cbz_EF
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKVR

Estimated binding specificities ?

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# IC=3.142 IC/col=0.628 n_of_columns=5 specificity:   
A |  13  24  54   0  96
C |  13  24  16  96   0
G |  57  24  13   0   0
T |  13  24  13   0   0
scan!

Dendrogram of similar interfaces ?

matrix format
  
  ----KGVT--RG--   L   +-----------------------------2c7a_B    
                       ! 
  --EAKG--KTRG--   L   !                             +4umm_A    
                       !         +-------------------1 
  ----KGVG--RG--   L --7         !                   +4tnt_B    
                       !      +--5 
  ----KGVT--RG--   L   !      !  !                    +5emc_A    
                       !      !  !                  +-2 
  --ECKGAGKGRG--   L   !      !  +------------------3 +1hcq_E    
                       +------6                     ! 
  --ECKGAGKT--RG   L          !                     +4aa6_B    
                              ! 
  CAECKG--KGRG--   L          !                +-----1cit_A    
                              +----------------4 
  --ECKGAG--RG--   L                           +-----4ond_A

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updated Mon Jun 29 19:29:27 2026