6c2s_C : 3D-footprint complex

structure name	TRANSCRIPTIONAL REPRESSOR, COUR, BOUND TO A 23-MER DNA DUPLEX (Transcriptional regulator, MarR family)
reference	Cogan et al. 'J. 293 11727 2018
source	Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009) / Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009)
experiment	X-ray (resolution=2.85, R-factor=0.218)
structural superfamily	"Winged helix" DNA-binding domain;
sequence family	MarR family;
multimeric complexes	6c2s_AD 6c2s_BC
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6c2s_C interface=65,66,67,68,70,92, selkmgelsellgyalkraqlrvfedflhcvapvqltpaqfsvlllldanpgrnqteiattlgiLRPNfVamldalegrglcvrtrspsdrRshilmltdkgratlarakklvatrhedrltellgrdnrdallsmlatiar
interface signature	LRPNVR

Estimated binding specificities ?

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# IC=6.292 IC/col=0.699 n_of_columns=9

specificity:

A |  73   0  24  24   7   7  73   0  96
C |   9   0  24  24   7   7   7   0   0
G |   7   0  24  24   9   7   9   0   0
T |   7  96  24  24  73  75   7  96   0

scan!

Dendrogram of similar interfaces ?

matrix format

  
  ----RGSTRTSTHG--------RA----   L           +-----------------------------3zpl_B    
                                           +-1 
  --DCLT--AGTTRG----RG--RA----   L       +-2 +-----------------------------5h3r_A    
                                         ! ! 
  ----RGTCTA--RGNT------RT----   L     +-3 +-----------------------------4fx4_B    
                                       ! ! 
  TT----KATTQTTG--LTRTKA--FTYT   L   +-4 +-----------------------------2p7c_B    
                                     ! ! 
  ----------------YG----------     --5 +-----------------------------3eyi_B    
                                     ! 
  --ITRGECSCSGKG--------------   L   +-----------------------------5i2d_R

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updated Sun Aug 3 11:01:14 2025