6c2s_C : 3D-footprint complex

structure name	TRANSCRIPTIONAL REPRESSOR, COUR, BOUND TO A 23-MER DNA DUPLEX (Transcriptional regulator, MarR family)
reference	Cogan et al. 'J. 293 11727 2018
source	Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009) / Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009)
experiment	X-ray (resolution=2.85, R-factor=0.218)
structural superfamily	"Winged helix" DNA-binding domain;
sequence family	MarR family;
multimeric complexes	6c2s_AD 6c2s_BC
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6c2s_C interface=65,66,67,68,70,92, selkmgelsellgyalkraqlrvfedflhcvapvqltpaqfsvlllldanpgrnqteiattlgiLRPNfVamldalegrglcvrtrspsdrRshilmltdkgratlarakklvatrhedrltellgrdnrdallsmlatiar
interface signature	LRPNVR

Estimated binding specificities ?

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# IC=6.338 IC/col=0.704 n_of_columns=9

specificity:

A |   0  96   7  75  73  24  24  96   9
C |   0   0   7   7   9  24  24   0   7
G |   0   0   7   7   7  24  24   0   7
T |  96   0  75   7   7  24  24   0  73

scan!

Dendrogram of similar interfaces ?

matrix format

  
  ----RGSTRTSTHG--------RA----   L                                     +3zpl_B    
                                               +-----------------------1 
  --DCLT--AGTTRG----RG--RA----   L       +-----2                       +5h3r_A    
                                         !     ! 
  --ITRGECSCSGKG--------------   L     +-3     +-----------------------5i2d_R    
                                       ! ! 
  TT----KATTQTTG--LTRTKA--FTYT   L   +-4 +-----------------------------2p7c_B    
                                     ! ! 
  ----RGTCTA--RGNT------RT----   L --5 +-----------------------------4fx4_B    
                                     ! 
  ----------------YG----------       +-----------------------------3eyi_B

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updated Fri Sep 13 21:23:45 2024