interface graph thumbnail
legend  pdf

structure namePROTEUS VULGARIS HIGA ANTITOXIN BOUND TO DNA
(Antitoxin HigA)
referenceSchureck et al. Mol.Microbiol. 111 1449 2019
sourceProteus vulgaris
experimentX-ray (resolution=2.90, R-factor=0.227)
structural superfamilylambda repressor-like DNA-binding domains;
sequence familyHelixturnhelix;
multimeric complexes6chv_AC 6chv_BD 6chv_GH
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRTASRT

Estimated binding specificities ?

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# IC=5.339 IC/col=0.763 n_of_columns=7 specificity:   
A |   0   0   9  69  67  24  96
C |   0   0  11   9  11  24   0
G |   0  96   9   9   9  24   0
T |  96   0  67   9   9  24   0
scan!

Dendrogram of similar interfaces ?

matrix format
  
  ----RTTT--AT--STRG----TT----   L               +--------6chv_D    
                                           +-----3 
  RT--------RG----NT----ETRTYA   L         !     !   +----7f9h_B    
                                           !     +---2 
  ----AT--QAAT--SA------------       +-----4         +----4z5h_A    
                                     !     ! 
  --QT--STNTVTATSTQTRTETTT----   L   !     !            +-2r1j_L    
                                   --5     +------------1 
  ------SGKGSCQTSTRG----------   L   !                  +-6w1a_A    
                                     ! 
  ----STKCQAAT--SA------------   L   +--------------------3dnv_B    
                                   

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updated Tue Dec 19 12:24:48 2023