interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF STREPTOCOCCUS DYSGALACTIAE SHP PHEROMONE RECEPTOR RGG2 BOUND TO DNA
(Transcriptional regulator)
referenceCapodagli et al. Proc.Natl.Acad.Sci.USA 117 24494 2020
sourceStreptococcus dysgalactiae
experimentX-ray (resolution=2.80, R-factor=0.236)
structural superfamilylambda repressor-like DNA-binding domains;
sequence familyHelixturnhelix;
multimeric complexes6w1a_AB
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSKSQSR

Estimated binding specificities ?

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# IC=3.101 IC/col=0.775 n_of_columns=4 specificity:   
A |   0  13   0  54
C |  96  54  96  13
G |   0  13   0  16
T |   0  16   0  13
scan!

Dendrogram of similar interfaces ?

matrix format
  
  ----SGKGSCQTSTRG------   L                                +6w1a_A    
                                                 +----------2 
  --CTSGKTSGQTSTRC------   L               +-----4          +6w1f_A    
                                           !     ! 
  ----HCQASTETSARG----VT   L        +------5     +----------3u3w_B    
                                    !      ! 
  ----TT--RGQTIT--------   L        !      +----------------5jub_B    
                               +----6 
  ----STNTVTATSTQTRTETTT   L   !    !                       +2r1j_L    
                               !    !                     +-1 
  AT--ATTTPTTTNT--------   L --7    +---------------------3 +6fix_D    
                               !                          ! 
  ----AAKGSGYGST--RTQG--   L   !                          +-3zkc_A    
                               ! 
  ------KGSGTTSTQC----QG   L   +----------------------------3zhm_A    
                             

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updated Wed Dec 18 06:25:13 2024