6w1a_A : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF STREPTOCOCCUS DYSGALACTIAE SHP PHEROMONE RECEPTOR RGG2 BOUND TO DNA (Transcriptional regulator)
reference	Capodagli et al. Proc.Natl.Acad.Sci.USA 117 24494 2020
source	Streptococcus dysgalactiae
experiment	X-ray (resolution=2.80, R-factor=0.236)
structural superfamily	lambda repressor-like DNA-binding domains;
sequence family	Helixturnhelix;
multimeric complexes	6w1a_AB
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6w1a_A interface=27,28,29,30,32,33, kelgktlrrlrqgkqvsissladehlSKSQiSRfergeseiscsrllnlldklnitidefvsthskththfftllsrvrkyyaeknvakllklledyahkdyestmikailssieptvepseeevtrltdylfsveqwgyyeiillgncsrfinyntlflltkemvtsfayseqnktnktlvtqlsincliisidysyfdhshyliekiefllrdelnfyektvflyvhgyyklkqgqvsgkddmrqalqifkylgedalyysykehyrkevlg
interface signature	SKSQSR

Estimated binding specificities ?

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# IC=3.101 IC/col=0.775 n_of_columns=4

specificity:

A |  13   0  13   0
C |  13   0  13   0
G |  16  96  54  96
T |  54   0  16   0

scan!

Dendrogram of similar interfaces ?

matrix format

  
  ----SGKGSCQTSTRG------   L                                +6w1a_A    
                                                 +----------2 
  --CTSGKTSGQTSTRC------   L               +-----4          +6w1f_A    
                                           !     ! 
  ----HCQASTETSARG----VT   L        +------5     +----------3u3w_B    
                                    !      ! 
  ----TT--RGQTIT--------   L        !      +----------------5jub_B    
                               +----6 
  ----STNTVTATSTQTRTETTT   L   !    !                       +2r1j_L    
                               !    !                     +-1 
  AT--ATTTPTTTNT--------   L --7    +---------------------3 +6fix_D    
                               !                          ! 
  ----AAKGSGYGST--RTQG--   L   !                          +-3zkc_A    
                               ! 
  ------KGSGTTSTQC----QG   L   +----------------------------3zhm_A

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updated Sun Aug 3 13:58:24 2025