| structure name | STRUCTURE OF CDX2-DNA(TCG) (Homeobox protein CDX-2) |
| reference | Morgunova et al. Elife 7 ? 2018 |
| source | Homo sapiens |
| experiment | X-ray (resolution=2.57, R-factor=0.222) |
| structural superfamily | Homeodomain-like; |
| sequence family | Homeobox domain; |
| redundant complexes | 5lty_K
6es2_K
 7q4n_C
|
| links to other resources | NAKB  PDIdb DNAproDB |
| protein sequence | |
| interface signature | YRIQN |
Estimated binding specificities ?
| readout + contact |  |
A | 9 9 0 96 11 C | 9 11 0 0 67 G | 11 9 0 0 9 T | 67 67 96 0 9scan! |
Related DNA sequences reported in the literature ?
| site | source | matches (E-value) |
|---|---|---|
| term: CDX2 | ||
| TATAAAA | PubMed | 5lty_M(1.09e-02), 6es2_K(1.05e-02) |
| GTTTAGA | PubMed | 5lty_M(1.09e-02), 6es2_K(1.05e-02) |
| TTTTAGG | PubMed | 5lty_M(1.09e-02), 6es2_K(1.05e-02) |
| GTTTATG | PubMed | 5lty_M(1.09e-02), 6es2_K(1.05e-02) |
Dendrogram of similar interfaces ?
matrix format----RA------YAQTNAAARG-- L +-----------------------------6wig_A ! KG--RT------IAQCNAYA--RT L ! +1nk2_P ! +------------------------3 RC--RT------NT--NAITRG-- +-9 ! +5zjt_B ! ! ! ----RT--RT--IAQCNA------ L ! ! ! +5jlw_D ! ! ! +-1 ----RT------NT--NAIARG-- L ! +---8 ! +1b72_B ! ! +-------------4 ----RT------ITQCNAACRG-- L ! ! ! ! +6a8r_A ! ! +-----6 +-2 --RC--RT----NCSTNARG---- L -10 ! ! ! +1mnm_C ! ! ! ! ----------RCVACTNAQA---- L ! +---7 +---------------7xrc_C ! ! ----RT----FTYAQTNAATRG-- L ! ! +----6ryd_F ! +----------------5 ----------RTVAITNAMCRG-- L ! +----1yrn_A ! --------------KC--YCFAKC +-----------------------------6p5a_B |
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updated Sun Aug 3 11:13:51 2025