3D-footprint cannot reliably estimate the specificity of histones, as they display few contacts over long stretches of DNA.

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updated Tue Jan 6 06:02:08 2026

structure name	HUMAN NUCLEOSOME CORE PARTICLE WITH COHESIVE END DNA TERMINI
reference	DeFalco et al. 'Nat 10 5751 2019
source	HOMO SAPIENS
experiment	X-ray (resolution=2.25, R-factor=?)
structural superfamily	Histone-fold;PH domain-like;lambda repressor-like DNA-binding domains;p53-like transcription factors;
reference complex	5o9g_F 6a5l_g 6r8y_H 6upk_H 6x0n_f 7ccr_A 7jzv_N 7lyb_G 7nkx_f 7u0g_M 7vdt_B 7xzx_N 8txv_G 8u14_G 8upf_G 8wg5_E
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6jxd_A interface=3,46, phRyrpgtvalreirryqkstellirklpfqrlvreiaqdfktdlRfqssavmalqeaceaylvglfedtnlcaihakrvtimpkdiqlarrirgera > 6jxd_B interface=23, rdniqgitkpairrlarrggvkRisgliyeetrgvlkvflenvirdavtytehakrktvtamdvvyalkrqgrtlygfgg > 6jxd_C interface=31, rkaktrssraglqfpvgrvhrllrkgnyseRvgagapvylaavleyltaeilelagnaardnkktriiprhlqlairndeelnkllgrvtiaqggvlpniqavllpk > 6jxd_D interface=5, rkrsRkesysiyvykvlkqvhpdtgisskamgimnsfvndiferiageasrlahynkrstitsreiqtavrlllpgelakhavsegtkavtkytsak > 6jxd_E interface=3,4, phRYrpgtvalreirryqkstellirklpfqrlvreiaqdfktdlrfqssavmalqeaceaylvglfedtnlcaihakrvtimpkdiqlarrirger > 6jxd_F interface= krHRkvlrdniqgitkpairrlarrggvkrisgliyeetrgvlkvflenvirdavtytehakrktvtamdvvyalkrqgrtlygfgg > 6jxd_G interface=5,30, kaktRssraglqfpvgrvhrllrkgnyseRvgagapvylaavleyltaeilelagnaardnkktriiprhlqlairndeelnkllgrvtiaqggvlpniqavllpk > 6jxd_H interface= rkrsRkesysiyvykvlkqvhpdtgisskAmgimnsfvndiferiageasrlahynkrstitsreiqtavrlllpgelakhavsegtkavtkytsak