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structure nameCRYSTAL STRUCTURE OF HUMAN DNMT3B-DNMT3L IN COMPLEX WITH DNA CONTAINING CPGPG SITE
(DNA CYTOSINE-5-METHYLTRANSFERASE 3B)
referenceChen et al. 'Nucleic 48 3949 2020
sourceHOMO SAPIENS
experimentX-ray (resolution=2.91, R-factor=0.189)
structural superfamilyS-adenosyl-L-methionine-dependent methyltransferases;
sequence familyC5 cytosinespecific DNA methylase 740;
multimeric complexes6kda_AD 6kdb_AD 6u8p_AD 6u8v_AD 6u8w_AD 6u8x_AD 6u90_AD 6u91_AD
reference complex6kdb_D
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureNVPQKSN

Estimated binding specificities ?

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# IC=2.917 IC/col=0.729 n_of_columns=4 specificity:   
A |  12  12   0   0
C |  12  12   0   0
G |  12  12  96  84
T |  60  60   0  12
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updated Fri Sep 13 00:03:35 2024