6ml4_A : 3D-footprint complex

structure name	BTB24 ZINC FINGERS 4-8 WITH 19+1MER DNA OLIGONUCLEOTIDE (SEQUENCE 3) (Zinc finger and BTB domain-containing protein 24)
reference	Horton et al. 'Nucleic 47 8388 2019
source	Mus musculus
experiment	X-ray (resolution=1.48, R-factor=0.192)
structural superfamily	beta-beta-alpha zinc fingers;
sequence family	Zinc finger, C2H2 type;
redundant complexes	6ml2_A 6ml3_A 6ml5_A 6ml6_A 6ml7_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6ml4_A interface=44,46,47,50,71,72,74,75,100,101,102,103,105,106,128,130,131, gsksftcdqcgkyfsqkrqlkshyrvhtghslpecshchrkfmDvSQlkKhlrthtgekpftceicgksfTAkSSlqthirihrgekpyscsicgkcfsDSSAkRRhcilhtgkkpfscpecglqfaRlDNlkahlkihskek
interface signature	DSQKTASSDSSARRRDN

Estimated binding specificities ?

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# IC=14.497 IC/col=1.115 n_of_columns=13

specificity:

A |  16  96   0   0   0   0   0   0   0   0  56   0   0
C |  64   0   0   0   0  88  96   8   0   0  16  96   0
G |   8   0  96  96   0   0   0   0  96  88   8   0  96
T |   8   0   0   0  96   8   0  88   0   8  16   0   0

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Dendrogram of similar interfaces ?

matrix format

  
  --DC--SCQGKTTTATSCSC----DCSGATRARGRGDCNA   L                   +-----------6ml4_A    
                                                     +-----------1 
  --DC--YCKGRG--QA--TC----RCSCDC--VT------   L     +-2           +-----------5k5i_A    
                                                   ! ! 
  RGST--YGYC----QCTGSTRGYT----------------       +-3 +-----------------------4is1_C    
                                                 ! ! 
  ------------------------QA--TC--RGRGYCRT   L --4 +-------------------------7txc_E    
                                                 ! 
  QT--AG--KGRG--RGDCKG--------------------   L   +--------------------------7n5w_A

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updated Fri Sep 13 22:37:51 2024